Evidence map›Paper›PMID 26703691›Full record

ArticleInternational journal of environmental research and public health2015

Persistent HIV Viremia: Description of a Cohort of HIV Infected Individuals with ART Failure in Puerto Rico.

Gerónimo Maldonado-Martínez, Robert F Hunter-Mellado, Diana Fernández-Santos, Eddy Ríos-Olivares

Abstract readComparative Study
In one paragraph

Article in International journal of environmental research and public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Dolutegravir based therapy showed CD4Scientific reports · 2024
    Article
  3. Overamped: Stimulant Use and HIV Pathogenesis.Current HIV/AIDS reports · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gerónimo Maldonado-MartínezData Management and Statistical Research Support Unit, Universidad Central del Caribe, Bayamón 00960, Puerto Rico. geronimo.maldonado@uccaribe.edu.
Robert F Hunter-MelladoInternal Medicine Department, Universidad Central del Caribe, Bayamón 00960, Puerto Rico. robert.hunter@uccaribe.edu.
Diana Fernández-SantosData Management and Statistical Research Support Unit, Universidad Central del Caribe, Bayamón 00960, Puerto Rico. diana.fernandez@uccaribe.edu.
Eddy Ríos-OlivaresMicrobiology Department, Universidad Central del Caribe, Bayamón 00960, Puerto Rico. eddy.rios@uccaribe.edu.

Funding

UNIVERSITY MEDICAL RESEARCH CENTERG12RR003035 · NCRR · UNIVERSIDAD CENTRAL DEL CARIBE · PI ROJAS, LEGIER V · 1986 to 2011
$26.7M
TECHNOLOGIES AND RESOURCES FOR CORE LABORATORIESU54MD007587 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI BENABE, JULIO E, LUCIANO, CARLOS A. · 2012 to 2018
$23.2M
UNIVERSIDAD CENTRAL DEL CARIBE BIOMEDICAL RESEARCH CENTERSG12MD007583 · NIMHD · UNIVERSIDAD CENTRAL DEL CARIBE · PI RODRIGUEZ, JOSE GINEL · 2012 to 2016
$8.4M
TRCLU54RR026139 · NCRR · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI FRONTERA, WALTER R. · 2010 to 2011
$8.4M
NCRR NIH HHS G12 RR003035NCRR NIH HHS G12RR-03035NCRR NIH HHS U54 RR026139NCRR NIH HHS U54RR026139NIMHD NIH HHS 8G12MD007583NIMHD NIH HHS 8U54MD007587NIMHD NIH HHS G12 MD007583NIMHD NIH HHS U54 MD007587
6 · The paper itself

Abstract

The introduction of antiretroviral therapy (ART) has allowed human immunodeficiency virus (HIV) suppression in patients. We present data of a cohort of Puerto Rican patients with HIV who were under treatment with a steady regime of ART across a time horizon of eleven years. The time periods were categorized into four year stratums: 2000 to 2002; 2003 to 2005; 2006 to 2008 and 2009 to 2011. Socio-demographic profile, HIV risk factors, co-morbid conditions were included as study variables. One year mortality was defined. The p value was set at ≤0.05. The cohort consisted of 882 patients with 661 subjects presenting with persistent HIV viral load after a self-reported 12 month history of ART use. In this sub-cohort a higher viral load was seen across time (p < 0.05). Illicit drug use, IV drug use, alcohol use, loss of work were associated to having higher viral load means (p < 0.05). HIV viral load mean was lower as BMI increased (p < 0.001). It is imperative to readdress antiretroviral adherence protocols and further study ART tolerance and compliance.

Indexed as

AdultAgedAged, 80 and overAge FactorsAnti-Retroviral AgentsCohort StudiesFemaleHIV InfectionsHumansMaleMiddle AgedPuerto RicoRisk FactorsSex FactorsSocioeconomic FactorsTime FactorsAnti-Retroviral AgentsARTHIVmean viral loadPuerto Ricoviremia

Identifiers

PMID26703691
PMCPMC4730441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.