Evidence map›Paper›PMID 26703660›Full record

ArticleInternational journal of environmental research and public health2015

Community-Based Participatory Research Integrates Behavioral and Biological Research to Achieve Health Equity for Native Hawaiians.

Claire K M Townsend, Adrienne Dillard, Kelsea K Hosoda, Gregory G Maskarinec, Alika K Maunakea, Sheryl R Yoshimura, Claire Hughes, Donna-Marie Palakiko, Bridget Puni Kehauoha, Joseph Keawe'aimoku Kaholokula

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of environmental research and public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  6. Developing principles of social change as a result of a Pasifika Youth Empowerment Program: A qualitative study.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2021
    Article
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  13. Insights in Public Health: FromHawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health · 2017
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Claire K M TownsendDepartment of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawai'i at Mānoa, 651 Ilalo Street, MEB 307L, Honolulu, HI 96813, USA. clairemt@hawaii.edu.
Adrienne DillardKula no na Po'e Hawai'i, P.O. Box 2368, Honolulu, HI 96823, USA. kula.papakolea@gmail.com.
Kelsea K HosodaDepartment of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawai'i at Mānoa, 651 Ilalo Street, MEB 307L, Honolulu, HI 96813, USA. clairemt@hawaii.edu.
Gregory G MaskarinecDepartment of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawai'i at Mānoa, 651 Ilalo Street, MEB 307L, Honolulu, HI 96813, USA. khosoda@hawaii.edu.
Alika K MaunakeaDepartment of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawai'i at Mānoa, 651 Ilalo Street, MEB 307L, Honolulu, HI 96813, USA. gregorym@hawaii.edu.
Sheryl R YoshimuraKōkua Kalihi Valley Comprehensive Family Services, 2239 N. School Street, Honolulu, HI 96819, USA. sryoshimura@gmail.com.
Claire HughesHawai'i Maoli, Association of Hawaiian Civic Clubs, P.O. Box 3866 Honolulu, HI 96812, USA. hughes1926@aol.com.
Donna-Marie PalakikoKe Ola Mamo, Dillingham Plaza, 1505 Dillingham Blvd #205, Honolulu, HI 96817, USA. dpalakiko@keolamamo.org.
Bridget Puni KehauohaKula no na Po'e Hawai'i, P.O. Box 2368, Honolulu, HI 96823, USA. punikekauoha@gmail.com.
Joseph Keawe'aimoku KaholokulaDepartment of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawai'i at Mānoa, 651 Ilalo Street, MEB 307L, Honolulu, HI 96813, USA. amaunake@hawaii.edu.
University of Hawaiʻi at Mānoa · USHawaii Medical Service Association · USKōkua Kalihi Valley · US

Funding

RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI HEDGES, JERRIS ROBERT, MOKUAU, NOREEN · 2012 to 2018
$21.1M
Transgenic Mouse, ICSI and IVF CoreP20GM103457 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI WARD, WILLIAM S · 2012 to 2018
$12.9M
PILI 'Ohana Project: Partnerships to Overcome Obesity Disparities in Hawai'iR24MD001660 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI KAHOLOKULA, JOSEPH KEAWE'AIMOKU · 2005 to 2015
$6.3M
Identifying Epigenetic Biomarkers of Cardiovascular Disease Risk In HumansK01HL125504 · NHLBI · UNIVERSITY OF HAWAII AT MANOA · PI MAUNAKEA, ALIKA KEOLAOKALANI · 2015 to 2018
$655k
NHLBI NIH HHS K01 HL125504NIGMS NIH HHS P20 GM103457NIMHD NIH HHS R24 MD001660NIMHD NIH HHS R24MD001660NIMHD NIH HHS U54 MD007584NIMHD NIH HHS U54MD007584
6 · The paper itself

Abstract

Native Hawaiians bear a disproportionate burden of type-2 diabetes and related complications compared to all other groups in Hawai'i (e.g., Whites, Japanese, Korean). Distrust in these communities is a significant barrier to participation in epigenetic research studies seeking to better understand disease processes. The purpose of this paper is to describe the community-based participatory research (CBPR) approach and research process we employed to integrate behavior and biological sciences with community health priorities. A CBPR approach was used to test a 3-month evidence-based, diabetes self-management intervention (N = 65). To investigate the molecular mechanisms linking inflammation with glucose homeostasis, a subset of participants (n = 16) provided peripheral blood mononuclear cells. Community and academic researchers collaborated on research design, assessment protocols, and participant recruitment, prioritizing participants' convenience and education and strictly limiting the use of the data collected. Preliminary results indicate significant changes in DNA methylation at gene regions associated with inflammation and diabetes signaling pathways and significant improvements in hemoglobin A1c, self-care activities, and diabetes distress and understanding. This study integrates community, behavioral, and epigenomic expertise to better understand the outcomes of a diabetes self-management intervention. Key lessons learned suggest the studies requiring biospecimen collection in indigenous populations require community trust of the researchers, mutual benefits for the community and researchers, and for the researchers to prioritize the community's needs. CBPR may be an important tool in providing communities the voice and protections to participate in studies requiring biospecimens.

Indexed as

Health EquityAdultAsian PeopleBiomedical ResearchCommunity-Based Participatory ResearchCommunity-Institutional RelationsDiabetes Mellitus, Type 2Evidence-Based MedicineFemaleHumansMaleMiddle AgedNative Hawaiian or Pacific IslanderPatient SelectionPublic HealthResearch Designcommunity-based participatory researchdiabetes self-managementepigenomicsNative Hawaiians

Identifiers

PMID26703660
PMCPMC4730395
OpenAlexW2215850858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.