Evidence map›Paper›PMID 26702851›Full record

ReviewCurrent opinion in endocrinology, diabetes, and obesity2016

Genomic insights into growth and its disorders: an update.

Christiaan de Bruin, Andrew Dauber

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current opinion in endocrinology, diabetes, and obesity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Short Stature is Progressive in Patients with Heterozygous NPR2 Mutations.The Journal of clinical endocrinology and metabolism · 2020
    Observational
  2. Review
  3. Human energy expenditure: advances in organ-tissue prediction models.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2018
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christiaan de BruinCincinnati Center for Growth Disorders, Division of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Andrew Dauber

Funding

Rare Genetic Variants as Novel Causes of Idopathic or Syndromic Short StatureK23HD073351 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI DAUBER, ANDREW NAHUM · 2012 to 2016
$664k
NICHD NIH HHS 5K23HD073351NICHD NIH HHS K23 HD073351
6 · The paper itself

Abstract

purpose of reviewThis article provides an update of the most striking new developments in the field of growth genetics over the past 12 months. RECENT

findingsA number of large genome-wide association studies have identified new genetic loci and pathways associated to human growth and adult height as well as related traits and comorbidities. New genetic causes of primordial dwarfism and several short stature syndromes have been elucidated. Moreover, a breakthrough finding of Xq26 microduplications as a cause of pituitary gigantism was made. Several new developments in imprinted growth-related genes (including the first human mutation in insulin-like growth factor II) and novel insights into the epigenetic regulation of growth have been reported. SUMMARY: Genomic investigations continue to provide new insights into the genetic basis of human growth as well as its disorders.

Indexed as

Genome-Wide Association StudyAggrecansAtrial Natriuretic Factor Receptor BBody HeightDwarfismGigantismGrowth DisordersHumansReceptors, Atrial Natriuretic FactorACAN protein, humanAggrecansAtrial Natriuretic Factor Receptor BReceptors, Atrial Natriuretic Factor

Identifiers

PMID26702851
PMCPMC4733875

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.