Finding the Middlemen in Genome Organization.

Xianrong Wong, Karen L Reddy

Abstract readComment

In one paragraph

Article in Developmental cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Mapping the micro-proteome of the nuclear lamina and lamina-associated domains.Life science alliance · 2021
Article
The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting.Journal of cell science · 2020
Article

4 · The record

Corrections and comments

Comment on
Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos.2015

5 · Who and what money

Authors and funding

2 authors.

Xianrong WongDepartment of Biological Chemistry, Center for Epigenetics, Johns Hopkins University, 855 N. Wolfe Street, Baltimore, MD 21205, USA.

Karen L ReddyDepartment of Biological Chemistry, Center for Epigenetics, Johns Hopkins University, 855 N. Wolfe Street, Baltimore, MD 21205, USA. Electronic address: kreddy4@jhmi.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromatin domains associated with the nuclear lamina are generally heterochromatic and transcriptionally repressed. How they are recruited to and maintained at the nuclear periphery remains unclear. A recent study by Gonzalez-Sandoval et al. (2015) in Cell identifies a chromatin-binding protein that links repressive chromatin with the inner nuclear membrane.

Indexed as

HeterochromatinHistone CodeAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsChromosomal Proteins, Non-HistoneEmbryo, NonmammalianCaenorhabditis elegans ProteinsChromosomal Proteins, Non-HistoneHeterochromatin

Identifiers

PMID26702826

DOI10.1016/j.devcel.2015.12.007

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.