ArticleMalaria journal2015
Acute kidney injury in imported Plasmodium falciparum malaria.
Article in Malaria journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
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Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Kidney and endothelial injury biomarkers as predictors of complications and mortality in patients with malaria: a systematic review.Malaria journal · 2026Pooled it
- Clinical characteristics and outcome of malaria-associated acute kidney injury in adult patients: a systematic review and meta analysis.Malaria journal · 2026Pooled it
- Immunomodulation Therapy to Treat Severe Malaria With Multiple Organ Failure.Critical care explorations · 2026Article
- Article
- Prevalence of acute kidney injury and its associated factors among malaria patients admitted to public hospitals in the Ilu Aba Bora and Bedelle Zones of Oromia region, Southwest Ethiopia.BMC infectious diseases · 2026Article
- Malaria-Associated Acute Kidney Injury in a Low-Endemic Region: A Case Series of Five ImportedCase reports in infectious diseases · 2026Article
- Evaluation of serum electrolytes and kidney function among untreated malaria (Plasmodium falciparum) patients in health centers, Konso zone, South Ethiopia.Tropical diseases, travel medicine and vaccines · 2025Article
- Severe Malaria Due toLife (Basel, Switzerland) · 2025Article
- High water turnover, hydration status, and heat stress among Daasanach pastoralists in a hot, semi-arid climate.Evolution, medicine, and public health · 2025Article
- The most lethal human protozoan parasite is plasmodium falciparum: severe malaria-associated acute renal failure - a case report.Annals of medicine and surgery (2012) · 2024Article
- Clinical characteristics and outcomes of patients on haemodialysis at Jimma medical center, Ethiopia: a 7-Year review.BMC nephrology · 2024Article
- Involvement of Inflammatory Cytokines, Renal NaPi-IIa Cotransporter, and TRAIL Induced-Apoptosis in Experimental Malaria-Associated Acute Kidney Injury.Pathogens (Basel, Switzerland) · 2024Article
- Total daily energy expenditure and elevated water turnover in a small-scale semi-nomadic pastoralist society from Northern Kenya.Annals of human biology · 2024Article
- Article
- Prophylaxis Failure and Successful Management of Delayed-Onset Malaria with Renal Complications: A Case Report with Oral Artemether-Lumefantrine Treatment.Reports (MDPI) · 2023Article
- Thrombotic microangiopathy after kidney transplantation: lessons from a transplant tourist.Journal of nephrology · 2023Article
- Novel Experimental Mouse Model to Study Malaria-Associated Acute Kidney Injury.Pathogens (Basel, Switzerland) · 2023Article
- Kidney complications of parasitic diseases.Nature reviews. Nephrology · 2022Review
- Falciparum malaria associated acute kidney injury with polyneuropathy and intra-arterial thrombosis (stroke).European journal of medical research · 2022Article
- Toxicological Evaluation and Protective Effects of Ethanolic Leaf Extract ofVeterinary medicine international · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute kidney injury (AKI) is a known complication of malaria, and is reported to occur in up to 40% of adult patients with a severe Plasmodium falciparum infection in endemic regions. To gain insight in the incidence and risk factors of AKI in imported P. falciparum malaria, a retrospective analysis was performed on a large cohort of mostly non-immune patients with imported P. falciparum malaria. Aiming to include not only severe but also milder forms of renal failure, the KDIGO criteria were used to define AKI.
methodsClinical and laboratory data from 485 consecutive cases of imported P. falciparum malaria were extracted from the Rotterdam Malaria Cohort database. Acute kidney injury (AKI) was defined using the KDIGO criteria. Univariate and multivariate logistic regression analyses were used to identify risk factors for AKI.
resultsAKI was seen in 39 (8%) of all patients and in 23 (38%) of the 61 patients with severe malaria. Eight patients eventually needed renal replacement therapy (RRT); seven of them already had AKI at presentation. Higher age, higher leucocyte count and thrombocytopaenia were independently-associated with AKI but their positive predictive values were relatively poor.
conclusionAKI was found to be a common complication in adults with imported P. falciparum necessitating RRT in only a small minority of patients. The use of the KDIGO staging allows early recognition of a decline in renal function.
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