Evidence map›Paper›PMID 26702655›Full record

ArticleCurrent biology : CB2015

Sperm Centrosomes: Kiss Your Asterless Goodbye, for Fertility's Sake.

Gerald Schatten, Tim Stearns

Abstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. The E3 ligase Poe promotes Pericentrin degradation.Molecular biology of the cell · 2023
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Gerald SchattenDepartments of Ob-Gyn-Repro Sci, Cell Biology & Bioengineering, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. Electronic address: gschatten@pdc.magee.edu.
Tim StearnsDepartments of Biology & Genetics, Stanford University, Stanford, CA 94305, USA. Electronic address: stearns@stanford.edu.
Stanford University · USUniversity of Pittsburgh · US

Funding

GAMMA TUBULIN AND CENTROSOME STRUCTURE AND FUNCTIONR01GM052022 · NIGMS · STANFORD UNIVERSITY · PI STEARNS, TIM · 1995 to 2017
$6.5M
NIGMS NIH HHS R01 GM052022
6 · The paper itself

Abstract

Centrosomes are reduced to their cores in sperm. Emerging molecular explanations for centrosome construction have now helped to elucidate the mechanism of their destruction in sperm. Since centrosome inaccuracies cause aneuploidies responsible for cancers, birth defects and infertility, this new insight into centrosome behavior has broad implications.

Indexed as

CentrosomeFertilizationFertilityHumansInfertilitySpermatozoa

Identifiers

PMID26702655
OpenAlexW2216521995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.