Evidence map›Paper›PMID 26702651›Full record

ArticleCurrent biology : CB2015

Polycystic Kidney Disease: Lessons Learned from Caenorhabditis elegans Mating Behavior.

Christopher J Ward, Madhulika Sharma

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christopher J WardDepartment of Internal Medicine, Division of Nephrology and Hypertension, University of Kansas Medical Center, Kansas City, KS 66103, USA. Electronic address: cward6@kumc.edu.
Madhulika SharmaDepartment of Internal Medicine, Division of Nephrology and Hypertension, University of Kansas Medical Center, Kansas City, KS 66103, USA.
University of Kansas Medical Center · US

Funding

Implications of Notch signaling in HIV associated nephropathyR01DK108433 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SHARMA, MADHULIKA · 2015 to 2019
$743k
NIDDK NIH HHS R01 DK108433
6 · The paper itself

Abstract

Male worm mating requires lov-1 and pkd-2 (homologs of the human polycystic kidney disease genes, PKD1 and PKD2), which are expressed in male-specific neurons. Transcriptomic analysis of these neurons now catalogs molecules involved in signaling and ectosome biogenesis, with implications for human PKD.

Indexed as

Sexual Behavior, AnimalAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsFemaleHumansMalePolycystic Kidney DiseasesTRPP Cation ChannelsCaenorhabditis elegans ProteinsLOV-1 protein, C elegansPKD-2 protein, C elegansTRPP Cation Channels

Identifiers

PMID26702651
PMCPMC6077978
OpenAlexW2200195174

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.