Evidence map›Paper›PMID 26702407›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2015

Correlations between quantitative fat-water magnetic resonance imaging and computed tomography in human subcutaneous white adipose tissue.

Aliya Gifford, Ronald C Walker, Theodore F Towse, E Brian Welch

Open access · bronzeAbstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Characterizing active and inactive brown adipose tissue in adult humans using PET-CT and MR imaging.American journal of physiology. Endocrinology and metabolism · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aliya GiffordVanderbilt University , Institute of Imaging Science, 1161 21st Avenue South, Medical Center North, AA-1105, Nashville, Tennessee 37235, United States ; Vanderbilt University , Chemical and Physical Biology Program, 1161 21st Avenue South, Medical Center North, AA 3105, Nashville, Tennessee 37235, United States.
Ronald C WalkerTennessee Valley VA Healthcare , Department of Medical Imaging, 1161 21st Avenue South, Medical Center North, CCC-1121, Nashville, Tennessee 37235, United States ; Vanderbilt University , School of Medicine, Department of Radiology and Radiological Sciences, 1161 21st Avenue South, Medical Center North, CCC-1121, Nashville, Tennessee 37235, United States.
Theodore F TowseVanderbilt University , Institute of Imaging Science, 1161 21st Avenue South, Medical Center North, AA-1105, Nashville, Tennessee 37235, United States ; Vanderbilt University , School of Medicine, Department of Physical Medicine and Rehabilitation, 2201 Children's Way #1014, Nashville, Tennessee 37235, United States.
E Brian WelchVanderbilt University , Institute of Imaging Science, 1161 21st Avenue South, Medical Center North, AA-1105, Nashville, Tennessee 37235, United States ; Vanderbilt University , School of Medicine, Department of Radiology and Radiological Sciences, 1161 21st Avenue South, Medical Center North, CCC-1121, Nashville, Tennessee 37235, United States.
Vanderbilt University · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Institutional Predoctoral Training Program in Biomedical Imaging ScienceT32EB014841 · NIBIB · VANDERBILT UNIVERSITY · PI GORE, JOHN C · 2013 to 2017
$771k
Brown Adipose Tissue Quantification Using Magnetic Resonance ImagingR21DK096282 · NIDDK · VANDERBILT UNIVERSITY · PI WELCH, E. BRIAN · 2012 to 2013
$379k
NCATS NIH HHS UL1 TR000445NIBIB NIH HHS T32 EB014841NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R21 DK096282
6 · The paper itself

Abstract

Beyond estimation of depot volumes, quantitative analysis of adipose tissue properties could improve understanding of how adipose tissue correlates with metabolic risk factors. We investigated whether the fat signal fraction (FSF) derived from quantitative fat-water magnetic resonance imaging (MRI) scans at 3.0 T correlates to CT Hounsfield units (HU) of the same tissue. These measures were acquired in the subcutaneous white adipose tissue (WAT) at the umbilical level of 21 healthy adult subjects. A moderate correlation exists between MRI- and CT-derived WAT values for all subjects, [Formula: see text], [Formula: see text], with a slope of [Formula: see text], (95% CI [Formula: see text]), indicating that a decrease of 1 HU equals a mean increase of 0.38% FSF. We demonstrate that FSF estimates obtained using quantitative fat-water MRI techniques correlate with CT HU values in subcutaneous WAT, and therefore, MRI-based FSF could be used as an alternative to CT HU for assessing metabolic risk factors.

Indexed as

fat quantificationfat signal fractionHounsfield unitsobesityquantitative biomarker

Identifiers

PMID26702407
PMCPMC4684077
OpenAlexW2209602645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.