Evidence map›Paper›PMID 26702404›Full record

ArticleToxics

Oxyradical Stress, Endocannabinoids, and Atherosclerosis.

Anberitha T Matthews, Matthew K Ross

Open access · goldAbstract read
In one paragraph

Article in Toxics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Chlorpyrifos and ΔCurrent research in toxicology · 2021
    Review
  4. Cells · 2020
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Herbs as an antioxidant arsenal for periodontal diseases.Journal of intercultural ethnopharmacology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anberitha T MatthewsCenter for Environmental Health Sciences, Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, P.O. Box 6100, Mississippi State, MS 39762, USA.
Matthew K RossCenter for Environmental Health Sciences, Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, P.O. Box 6100, Mississippi State, MS 39762, USA.
Mississippi State University · US

Funding

Lipid glyceryl ester homeostasis in macrophages and perturbation by environmentalR15ES015348 · NIEHS · MISSISSIPPI STATE UNIVERSITY · PI ROSS, MATTHEW K · 2007 to 2012
$779k
Role of Endocannabinoids in AtherosclerosisF31HL122082 · NHLBI · MISSISSIPPI STATE UNIVERSITY · PI MATTHEWS, ANBERITHA T · 2014 to 2015
$47k
NHLBI NIH HHS F31 HL122082NIEHS NIH HHS R15 ES015348
6 · The paper itself

Abstract

Atherosclerosis is responsible for most cardiovascular disease (CVD) and is caused by several factors including hypertension, hypercholesterolemia, and chronic inflammation. Oxidants and electrophiles have roles in the pathophysiology of atherosclerosis and the concentrations of these reactive molecules are an important factor in disease initiation and progression. Overactive NADPH oxidase (Nox) produces excess superoxide resulting in oxidized macromolecules, which is an important factor in atherogenesis. Although superoxide and reactive oxygen species (ROS) have obvious toxic properties, they also have fundamental roles in signaling pathways that enable cells to adapt to stress. In addition to inflammation and ROS, the endocannabinoid system (eCB) is also important in atherogenesis. Linkages have been postulated between the eCB system, Nox, oxidative stress, and atherosclerosis. For instance, CB

Indexed as

2-arachidonoylglycerolanandamideatherogenesiscardiovascular diseaseNADPH oxidasereactive oxygen species

Identifiers

PMID26702404
PMCPMC4686160
OpenAlexW2186613088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.