ArticleJournal of pediatric intensive care
Optimizing Sedation Management to Promote Early Mobilization for Critically Ill Children.
Article in Journal of pediatric intensive care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Daily Sedation Interruption vs Continuous Sedation in Pediatric Patients Receiving Mechanical Ventilation: A Systematic Review and Meta-analysis.JAMA network open · 2024Pooled it
- Non-pharmacological interventions for sleep promotion in hospitalized children.The Cochrane database of systematic reviews · 2022Pooled it
- Early mobilization protocols for critically ill pediatric patients: systematic review.Revista Brasileira de terapia intensiva · 2019Pooled it
- Hydromorphone in Pediatric Pain Management: Pharmacology, Clinical Applications, and Safety Considerations-A Narrative Review.Healthcare (Basel, Switzerland) · 2026Review
- Speech-language pathologist involvement in the paediatric intensive care unit.International journal of speech-language pathology · 2024Article
- Cost-Benefit Analysis of a Pediatric ICU Sedation Weaning Protocol.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024Article
- Article
- Early Mobilization in Pediatric Critical Care: Exploring the Gap Between Theory and Practice in Saudi Arabia.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Analgesia and sedation in critically ill pediatric patients: an update from the recent guidelines and point of view.European journal of pediatrics · 2023Review
- Sleep cycle in children with severe acute bronchopneumonia during mechanical ventilation at different depths of sedation.BMC pediatrics · 2022Article
- Building a culture of early mobilization in the pediatric intensive care unit-a nuts and bolts approach.Translational pediatrics · 2021Review
- Current State of Analgesia and Sedation in the Pediatric Intensive Care Unit.Journal of clinical medicine · 2021Review
- MONISEDA Project: Improving Analgosedation Monitoring in Spanish Pediatric Intensive Care Units.Frontiers in pediatrics · 2021Article
- Botulism in the Pediatric Intensive Care Units in the United States: Interrogating a National Database.Journal of pediatric intensive care · 2020Article
- Practices related to assessment of sedation, analgesia and delirium among critical care pediatricians in Brazil.Einstein (Sao Paulo, Brazil) · 2020Article
- Early mobilization in the pediatric intensive care unit.Translational pediatrics · 2018Review
- Child Psychiatry Engagement in the Management of Delirium in Critically Ill Children.Critical care research and practice · 2018Article
- Physical and occupational therapy utilization in a pediatric intensive care unit.Journal of critical care · 2017Article
- Sedation in Critically Ill Children with Respiratory Failure.Frontiers in pediatrics · 2016Review
- Development and Implementation of Pediatric ICU-based Mobility Guidelines: A Quality Improvement Initiative.Pediatric quality & safetyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Achieving successful early mobilization for the intubated, critically ill child is dependent on optimizing sedation and analgesia. Finding the fine balance between oversedation and undersedation can be challenging. The ideal is for a child to be lucid and interactive during the daytime and demonstrate normal circadian rhythm for sleep with rest at night. Being alert during the day facilitates active participation in therapy including potential ambulation, while decreasing the risk of delirium during mechanical ventilation. An active state during the day with frequent mobilization promotes restorative sleep at night, which brings with it multiple benefits for healing and recovery. Indeed, this ideal may not be physiologically feasible given a child's critical illness and trajectory, but defining it as the "gold standard" for early mobilization provides a consistent goal for the pediatric intensive care unit (PICU) hospitalization. As such, goal-directed, patient-specific sedation plans are integral to creating a culture of mobility in the PICU. We review currently available sedation strategies for mechanically ventilated children for successful implementation of early mobilization in the PICU, as well as pharmacologic considerations for specific classes of sedative-analgesics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.