Evidence map›Paper›PMID 26702302›Full record

ReviewSystems and synthetic biology2015

Recent advances and versatility of MAGE towards industrial applications.

Vijai Singh, Darren Braddick

Abstract readReview
In one paragraph

Review in Systems and synthetic biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Rewriting the Genetic Code.Annual review of microbiology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Vijai SinghInstitute of Systems and Synthetic Biology, Université d'Évry Val d'Essonne, Genopole Campus 1, Batiment Genavenir 6, 5 rue Henri Desbruères, 91030 Évry, France.
Darren BraddickInstitute of Systems and Synthetic Biology, Université d'Évry Val d'Essonne, Genopole Campus 1, Batiment Genavenir 6, 5 rue Henri Desbruères, 91030 Évry, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genome engineering toolkit has expanded significantly in recent years, allowing us to study the functions of genes in cellular networks and assist in over-production of proteins, drugs, chemicals and biofuels. Multiplex automated genome engineering (MAGE) has been recently developed and gained more scientific interest towards strain engineering. MAGE is a simple, rapid and efficient tool for manipulating genes simultaneously in multiple loci, assigning genetic codes and integrating non-natural amino acids. MAGE can be further expanded towards the engineering of fast, robust and over-producing strains for chemicals, drugs and biofuels at industrial scales.

Indexed as

BiofuelsChemicalsDrugsGenomeMultiplex automated genome engineering

Identifiers

PMID26702302
PMCPMC4688408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.