Evidence map›Paper›PMID 26702174›Full record

ArticleIndian journal of psychological medicine

Effect of Transcranial Direct Current Stimulation on Prefrontal Inhibition in Schizophrenia Patients with Persistent Auditory Hallucinations: A Study on Antisaccade Task Performance.

Aditi Subramaniam, Sri Mahavir Agarwal, Sunil Kalmady, Venkataram Shivakumar, Harleen Chhabra, Anushree Bose, Dinakaran Damodharan, Janardhanan C Narayanaswamy, Sam B Hutton, Ganesan Venkatasubramanian

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In one paragraph

Article in Indian journal of psychological medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Aditi SubramaniamDepartment of Psychiatry, The Schizophrenia Clinic, Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
Sri Mahavir AgarwalDepartment of Psychiatry, The Schizophrenia Clinic, Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
Sunil KalmadyDepartment of Psychiatry, The Schizophrenia Clinic, Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
Venkataram ShivakumarDepartment of Psychiatry, The Schizophrenia Clinic, Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
Harleen ChhabraDepartment of Psychiatry, The Schizophrenia Clinic, Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
Anushree BoseDepartment of Psychiatry, The Schizophrenia Clinic, Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
Dinakaran DamodharanDepartment of Psychiatry, The Schizophrenia Clinic, Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
Janardhanan C NarayanaswamyDepartment of Psychiatry, The Schizophrenia Clinic, Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
Sam B HuttonUniversity of Sussex, Brighton, United Kingdom.
Ganesan VenkatasubramanianDepartment of Psychiatry, The Schizophrenia Clinic, Translational Psychiatry Laboratory, Neurobiology Research Centre, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
National Institute of Mental Health and Neurosciences · INUniversity of Sussex · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeficient prefrontal cortex inhibitory control is of particular interest with regard to the pathogenesis of auditory hallucinations (AHs) in schizophrenia. Antisaccade task performance is a sensitive index of prefrontal inhibitory function and has been consistently found to be abnormal in schizophrenia.

methodsThis study investigated the effect of transcranial direct current stimulation (tDCS) on antisaccade performance in 13 schizophrenia patients.

resultsThe tDCS resulted in significant reduction in antisaccade error percentage (t = 3.4; P = 0.005), final eye position gain (t = 2.3; P = 0.042), and AHs severity (t = 4.1; P = 0.003).

conclusionOur results raise the possibility that improvement in antisaccade performance and severity of AH may be mechanistically related.

Indexed as

Antisaccadehallucinationsschizophreniatranscranial direct current stimulation

Identifiers

PMID26702174
PMCPMC4676208
OpenAlexW1866082352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.