ArticleProceedings. Biological sciences2015
Artificial selection on introduced Asian haplotypes shaped the genetic architecture in European commercial pigs.
Article in Proceedings. Biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Genome-wide association studies and meta-analysis uncovers new candidate genes for growth and carcass traits in pigs.PloS one · 2018Pooled it
- The impact of haplotypes derived from Chinese pigs on genetic variation and economic traits in the Duroc breed.Genetics, selection, evolution : GSE · 2025Article
- Whole-genome resequencing reveals positive selection and introgression signatures and genetic loci associated with early puberty traits in Chinese indigenous pigs.Genetics, selection, evolution : GSE · 2025Article
- Integrative Analysis of Transcriptomic and Lipidomic Profiles Reveals a Differential Subcutaneous Adipose Tissue Mechanism among Ningxiang Pig and Berkshires, and Their Offspring.Animals : an open access journal from MDPI · 2023Article
- The pig pangenome provides insights into the roles of coding structural variations in genetic diversity and adaptation.Genome research · 2023Article
- Young SINEs in pig genomes impact gene regulation, genetic diversity, and complex traits.Communications biology · 2023Article
- Whole-genome analysis reveals the hybrid formation of Chinese indigenous DHB pig following human migration.Evolutionary applications · 2022Article
- Population genomic, olfactory, dietary, and gut microbiota analyses demonstrate the unique evolutionary trajectory of feral pigs.Molecular ecology · 2022Article
- Association Studies and Genomic Prediction for Genetic Improvements in Agriculture.Frontiers in plant science · 2022Review
- Accelerated deciphering of the genetic architecture of agricultural economic traits in pigs using a low-coverage whole-genome sequencing strategy.GigaScience · 2021Article
- Animal domestication in the era of ancient genomics.Nature reviews. Genetics · 2020Review
- Whole-genome sequencing of European autochthonous and commercial pig breeds allows the detection of signatures of selection for adaptation of genetic resources to different breeding and production systems.Genetics, selection, evolution : GSE · 2020Article
- Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics.BMC biology · 2019Review
- Harnessing genomic information for livestock improvement.Nature reviews. Genetics · 2019Review
- Introgression of Chinese haplotypes contributed to the improvement of Danish Duroc pigs.Evolutionary applications · 2019Article
- Genomic analysis reveals genes affecting distinct phenotypes among different Chinese and western pig breeds.Scientific reports · 2018Article
- Article
- RAPID COMMUNICATION: A haplotype information theory method reveals genes of evolutionary interest in European vs. Asian pigs.Journal of animal science · 2018Article
- Analysis of the genetic variation in mitochondrial DNA, Y-chromosome sequences, and MC1R sheds light on the ancestry of Nigerian indigenous pigs.Genetics, selection, evolution : GSE · 2017Article
- A decade of pig genome sequencing: a window on pig domestication and evolution.Genetics, selection, evolution : GSE · 2016Review
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Early pig farmers in Europe imported Asian pigs to cross with their local breeds in order to improve traits of commercial interest. Current genomics techniques enabled genome-wide identification of these Asian introgressed haplotypes in modern European pig breeds. We propose that the Asian variants are still present because they affect phenotypes that were important for ancient traditional, as well as recent, commercial pig breeding. Genome-wide introgression levels were only weakly correlated with gene content and recombination frequency. However, regions with an excess or absence of Asian haplotypes (AS) contained genes that were previously identified as phenotypically important such as FASN, ME1, and KIT. Therefore, the Asian alleles are thought to have an effect on phenotypes that were historically under selection. We aimed to estimate the effect of AS in introgressed regions in Large White pigs on the traits of backfat (BF) and litter size. The majority of regions we tested that retained Asian deoxyribonucleic acid (DNA) showed significantly increased BF from the Asian alleles. Our results suggest that the introgression in Large White pigs has been strongly determined by the selective pressure acting upon the introgressed AS. We therefore conclude that human-driven hybridization and selection contributed to the genomic architecture of these commercial pigs.
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Registered trials
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