Evidence map›Paper›PMID 26702029›Full record

SynthesisPediatrics2016

Kangaroo Mother Care and Neonatal Outcomes: A Meta-analysis.

Ellen O Boundy, Roya Dastjerdi, Donna Spiegelman, Wafaie W Fawzi, Stacey A Missmer, Ellice Lieberman, Sandhya Kajeepeta, Stephen Wall, Grace J Chan

Registry-linked trialOpen access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02645526 (Is a Woolen Cap Effective in Maintaining Normothermia in Preterm Infants During Kangaroo Mother Care?), which is not on this map. Cited by 254 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
254citing papers in PubMed, 15 pooled it
58.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02645526 phase4completednot on this map

Is a Woolen Cap Effective in Maintaining Normothermia in Preterm Infants During Kangaroo Mother Care?

TypeinterventionalSponsorUniversity Hospital PadovaRan2016 to 2016Enrolled300ConditionsNeonatal Temperature, Kangaroo Mother CareArmsWoolen cap
3 · Its place in the literature

Who cites it

254 citing papers in PubMed, 15 syntheses or guidelines pooled it, 660 citations in OpenAlex.

  1. Pooled it
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  7. Oral dextrose gel to prevent hypoglycaemia in at-risk neonates.The Cochrane database of systematic reviews · 2023
    Pooled it
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  9. [Evidence-based guideline for neonatal pain management in China (2023)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Guideline
  10. Effect of Non-Pharmacological Methods in the Reduction of Neonatal Pain: Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023
    Pooled it
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  14. Oral dextrose gel to prevent hypoglycaemia in at-risk neonates.The Cochrane database of systematic reviews · 2021
    Pooled it
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  16. The effect of maternal position on cerebral oxygenation in premature infants during Kangaroo care: a randomised controlled trial.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Trial
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194 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Ellen O BoundyDepartments of Epidemiology, grace.chan@childrens.harvard.edu.
Roya DastjerdiDepartments of Global Health and Population, and.
Donna SpiegelmanDepartments of Epidemiology, Departments of Global Health and Population, and Biostatistics, and.
Wafaie W FawziDepartments of Epidemiology, Departments of Global Health and Population, and Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts;
Stacey A MissmerDepartments of Epidemiology, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital, Boston, Massachusetts;
Ellice LiebermanDepartments of Epidemiology, Social and Behavioral Sciences, Harvard School of Public Health, Boston, Massachusetts; Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, Massachusetts;
Sandhya KajeepetaDepartments of Epidemiology.
Stephen WallSave the Children, Washington, DC; and.
Grace J ChanDepartments of Global Health and Population, and Save the Children, Washington, DC; and Department of Medicine, Boston Children's Hospital, Boston, Massachusetts.
Institute of Population, Health and Development · VNBrigham and Women's Hospital · USCancer Research And Biostatistics · USHarvard Global Health Institute · USHarvard University · USSave the Children · US

Funding

Predoctoral Training Program in Reproductive, Perinatal & Pediatric EpidemiologyT32HD060454 · NICHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI MICHELS, KARIN B · 2010 to 2014
$1.1M
NICHD NIH HHS T32 HD060454NICHD NIH HHS T32HD060454PHS HHS T76MC00001
6 · The paper itself

Abstract

contextKangaroo mother care (KMC) is an intervention aimed at improving outcomes among preterm and low birth weight newborns.

objectiveConduct a systematic review and meta-analysis estimating the association between KMC and neonatal outcomes. DATA SOURCES: PubMed, Embase, Web of Science, Scopus, African Index Medicus (AIM), Latin American and Caribbean Health Sciences Information System (LILACS), Index Medicus for the Eastern Mediterranean Region (IMEMR), Index Medicus for the South-East Asian Region (IMSEAR), and Western Pacific Region Index Medicus (WPRIM). STUDY SELECTION: We included randomized trials and observational studies through April 2014 examining the relationship between KMC and neonatal outcomes among infants of any birth weight or gestational age. Studies with <10 participants, lack of a comparison group without KMC, and those not reporting a quantitative association were excluded. DATA EXTRACTION: Two reviewers extracted data on study design, risk of bias, KMC intervention, neonatal outcomes, relative risk (RR) or mean difference measures.

results1035 studies were screened; 124 met inclusion criteria. Among LBW newborns, KMC compared to conventional care was associated with 36% lower mortality(RR 0.64; 95% [CI] 0.46, 0.89). KMC decreased risk of neonatal sepsis (RR 0.53, 95% CI 0.34, 0.83), hypothermia (RR 0.22; 95% CI 0.12, 0.41), hypoglycemia (RR 0.12; 95% CI 0.05, 0.32), and hospital readmission (RR 0.42; 95% CI 0.23, 0.76) and increased exclusive breastfeeding (RR 1.50; 95% CI 1.26, 1.78). Newborns receiving KMC had lower mean respiratory rate and pain measures, and higher oxygen saturation, temperature, and head circumference growth. LIMITATIONS: Lack of data on KMC limited the ability to assess dose-response.

conclusionsInterventions to scale up KMC implementation are warranted.

Indexed as

Kangaroo-Mother Care MethodHumansInfant, NewbornObservational Studies as TopicRandomized Controlled Trials as Topic

Identifiers

PMID26702029
PMCPMC4702019
OpenAlexW2212414619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.