ArticleBiology letters2015
Translocation of bacteria from the gut to the eggs triggers maternal transgenerational immune priming in Tribolium castaneum.
Article in Biology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 65 citations in OpenAlex.
- Strain-dependent resistance of yellow mealworm (Coleoptera: Tenebrionidae) to bacterial infection with and without probiotic supplementation.Journal of economic entomology · 2026Article
- Article
- Current insights into insect immune memory.eLife · 2025Review
- Multigenerational inheritance of parasitic stress memory inEnvironmental epigenetics · 2025Article
- Evidence for trans-generational immune priming againstFrontiers in immunology · 2025Article
- Article
- Trans-generational immune priming against American Foulbrood does not affect the performance of honeybee colonies.Frontiers in veterinary science · 2023Article
- Immune function of the serosa in hemimetabolous insect eggs.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Interaction of Liberibacter Solanacearum with Host Psyllid Vitellogenin and Its Association with Autophagy.Microbiology spectrum · 2022Article
- Review
- Immune priming: the secret weapon of the insect world.Virulence · 2020Review
- Transcriptomics reveals specific molecular mechanisms underlying transgenerational immunity inEcology and evolution · 2020Article
- Deciphering the molecular mechanisms of mother-to-egg immune protection in the mealworm beetle Tenebrio molitor.PLoS pathogens · 2020Article
- Parental Microbiota Modulates Offspring Development, Body Mass and Fecundity in a Polyphagous Fruit Fly.Microorganisms · 2020Article
- Article
- Article
- The costs of the immune memory within generations.Die Naturwissenschaften · 2019Article
- Immune Defenses of a Beneficial Pest: The Mealworm Beetle,Frontiers in physiology · 2019Review
- Epigenetic Mechanisms Are Involved in Sex-SpecificFrontiers in physiology · 2019Article
- Trans-generational Immune Priming in Invertebrates: Current Knowledge and Future Prospects.Frontiers in immunology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Invertebrates can be primed to enhance their protection against pathogens they have encountered before. This enhanced immunity can be passed maternally or paternally to the offspring and is known as transgenerational immune priming. We challenged larvae of the red flour beetle Tribolium castaneum by feeding them on diets supplemented with Escherichia coli, Micrococcus luteus or Pseudomonas entomophila, thus mimicking natural exposure to pathogens. The oral uptake of bacteria induced immunity-related genes in the offspring, but did not affect the methylation status of the egg DNA. However, we observed the translocation of bacteria or bacterial fragments from the gut to the developing eggs via the female reproductive system. Such translocating microbial elicitors are postulated to trigger bacterial strain-specific immune responses in the offspring and provide an alternative mechanistic explanation for maternal transgenerational immune priming in coleopteran insects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.