Evidence map›Paper›PMID 26700291›Full record

Trial reportBMJ open2015

Clinical effectiveness and cost-effectiveness of the Rehabilitation Enablement in Chronic Heart Failure (REACH-HF) facilitated self-care rehabilitation intervention in heart failure patients and caregivers: rationale and protocol for a multicentre randomised controlled trial.

R S Taylor, C Hayward, V Eyre, J Austin, R Davies, P Doherty, K Jolly, J Wingham, R Van Lingen, C Abraham and 9 more

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 6 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 6 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2019
    Pooled it
  5. Disease management interventions for heart failure.The Cochrane database of systematic reviews · 2019
    Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 9 institutions in 1 country.

R S TaylorInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
C HaywardPeninsula Clinical Trials Unit, Plymouth University, Plymouth, Devon, UK.
V EyrePeninsula Clinical Trials Unit, Plymouth University, Plymouth, Devon, UK.
J AustinHeart Failure Services and Cardiac Rehabilitation, Aneurin Bevan University Health Board, Nevill Hall Hospital, Abergavenny, UK.
R DaviesCardiology Department, Sandwell & West Birmingham Hospitals NHS Trust, Birmingham, UK.
P DohertyDepartment of Health Sciences, University of York, York, UK.
K JollyInstitute for Applied Health Research, University of Birmingham, Birmingham, UK.
J WinghamInstitute of Health Research, University of Exeter Medical School, Exeter, UK Department of Research, Development & Innovation, Royal Cornwall Hospitals NHS Trust, Truro, UK.
R Van LingenCardiology Department, Royal Cornwall Hospitals NHS Trust, Truro, UK.
C AbrahamPsychology Applied to Health Group, University of Exeter Medical School, Exeter, UK.
C GreenInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
F C WarrenInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
N BrittenInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
C J GreavesInstitute of Health Research, University of Exeter Medical School, Exeter, UK.
S SinghCentre for Exercise and Rehabilitation Science, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK.
S BuckinghamDepartment of Research, Development & Innovation, Royal Cornwall Hospitals NHS Trust, Truro, UK.
K PaulREACH-HF Patient and Public Involvement Group, c/o Research, Development & Innovation, Royal Cornwall Hospitals NHS Trust, Truro, UK.
H DalalInstitute of Health Research, University of Exeter Medical School, Exeter, UK Department of Research, Development & Innovation, Royal Cornwall Hospitals NHS Trust, Truro, UK.
REACH-HF Investigators
University of Exeter · GBRoyal Cornwall Hospital Trust · GBUniversity of Plymouth · GBNevill Hall Hospital · GBRoyal Cornwall Hospital · GBSandwell & West Birmingham Hospitals NHS Trust · GBUniversity Hospitals of Leicester NHS Trust · GBUniversity of Birmingham · GBUniversity of York · GB

Funding

Department of Health RP-PG-1210-12004Department of Health WMCLAHRC-2014-1
6 · The paper itself

Abstract

introductionThe Rehabilitation EnAblement in CHronic Heart Failure (REACH-HF) trial is part of a research programme designed to develop and evaluate a health professional facilitated, home-based, self-help rehabilitation intervention to improve self-care and health-related quality of life in people with heart failure and their caregivers. The trial will assess the clinical effectiveness and cost-effectiveness of the REACH-HF intervention in patients with systolic heart failure and impact on the outcomes of their caregivers. METHODS AND ANALYSIS: A parallel two group randomised controlled trial with 1:1 individual allocation to the REACH-HF intervention plus usual care (intervention group) or usual care alone (control group) in 216 patients with systolic heart failure (ejection fraction <45%) and their caregivers. The intervention comprises a self-help manual delivered by specially trained facilitators over a 12-week period. The primary outcome measure is patients' disease-specific health-related quality of life measured using the Minnesota Living with Heart Failure questionnaire at 12 months' follow-up. Secondary outcomes include survival and heart failure related hospitalisation, blood biomarkers, psychological well-being, exercise capacity, physical activity, other measures of quality of life, patient safety and the quality of life, psychological well-being and perceived burden of caregivers at 4, 6 and 12 months' follow-up. A process evaluation will assess fidelity of intervention delivery and explore potential mediators and moderators of changes in health-related quality of life in intervention and control group patients. Qualitative studies will describe patient and caregiver experiences of the intervention. An economic evaluation will estimate the cost-effectiveness of the REACH-HF intervention plus usual care versus usual care alone in patients with systolic heart failure. ETHICS AND DISSEMINATION: The study is approved by the North West-Lancaster Research Ethics Committee (ref 14/NW/1351). Findings will be disseminated via journals and presentations to publicise the research to clinicians, commissioners and service users. TRIAL REGISTRATION NUMBER: ISRCTN86234930; Pre-results.

Indexed as

Quality of LifeAdolescentAdultAgedAged, 80 and overCaregiversChronic DiseaseClinical ProtocolsCost-Benefit AnalysisFemaleFollow-Up StudiesHeart FailureHumansMaleMiddle AgedSelf CareREHABILITATION MEDICINE

Identifiers

PMID26700291
PMCPMC4691763
OpenAlexW2200999639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.