Trial reportBMJ open2015
First results about recovery of walking function in patients with intensive care unit-acquired muscle weakness from the General Weakness Syndrome Therapy (GymNAST) cohort study.
Trial report in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Trial
- Trial
- Effects that passive cycling exercise have on muscle strength, duration of mechanical ventilation, and length of hospital stay in critically ill patients: a randomized clinical trial.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaTrial
- Impact of Early Rehabilitation Initiation on Walking Recovery in Critically Ill Patients.Cureus · 2025Article
- Article
- Comprehensive assessment and progression of health status during neurorehabilitation in survivors of critical illness: a prospective cohort study.Annals of intensive care · 2024Article
- Pre-Admission Predictors of Walking Independence in Critically Ill Patients.Respiratory care · 2024Article
- Balance function in critical illness survivors and evaluation of psychometric properties of the Mini-BESTest.Scientific reports · 2024Article
- Association between the early mobilization of mechanically ventilated patients and independence in activities of daily living at hospital discharge.Scientific reports · 2023Article
- The association of macronutrient deficit with functional status at discharge from the intensive care unit: a retrospective study from a single-center critical illness registry.European journal of clinical nutrition · 2022Article
- Article
- Longtime Neurologic Outcome of Extracorporeal Membrane Oxygenation and Non Extracorporeal Membrane Oxygenation Acute Respiratory Distress Syndrome Survivors.Journal of clinical medicine · 2019Article
- International Classification of Functioning, Disability, and Health Domains of 60 Physical Functioning Measurement Instruments Used During the Adult Intensive Care Unit Stay: A Scoping Review.Physical therapy · 2019Article
- A multimodal rehabilitation program for patients with ICU acquired weakness improves ventilator weaning and discharge home.Journal of critical care · 2018Article
- Article
- [Course of rehabilitation in early neurological/neurosurgical rehabilitation. Results of a 2014 multi-center evaluation in Germany].Der Nervenarzt · 2016Article
- Brazilian version of the Functional Status Score for the ICU: translation and cross-cultural adaptation.Revista Brasileira de terapia intensivaArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo describe the time course of recovery of walking function and other activities of daily living in patients with intensive care unit (ICU)-acquired muscle weakness.
designThis is a cohort study.
participantsWe included critically ill patients with ICU-acquired muscle weakness.
settingPost-acute ICU and rehabilitation units in Germany. MEASURES: We measured walking function, muscle strength, activities in daily living, motor and cognitive function.
resultsWe recruited 150 patients (30% female) who fulfilled our inclusion and exclusion criteria. The primary outcome recovery of walking function was achieved after a median of 28.5 days (IQR=45) after rehabilitation onset and after a median of 81.5 days (IQR=64) after onset of illness. Our final multivariate model for recovery of walking function included two clinical variables from baseline: the Functional Status Score ICU (adjusted HR=1.07 (95% CI 1.03 to 1.12) and the ability to reach forward in cm (adjusted HR=1.02 (95% CI 1.00 to 1.04). All secondary outcomes but not pain improved significantly in the first 8 weeks after study onset.
conclusionsWe found good recovery of walking function for most patients and described the recovery of walking function of people with ICU-acquired muscle weakness. TRIALS REGISTRATIONS NUMBER: Sächsische Landesärztekammer EK-BR-32/13-1; DRKS00007181, German Register of Clinical Trials.
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