ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2016
Financial Concerns About Participation in Clinical Trials Among Patients With Cancer.
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In one paragraph
Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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25citing papers in PubMed, 1 pooled it
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Financial Burdens of Cancer Treatment: A Systematic Review of Risk Factors and Outcomes.Journal of the National Comprehensive Cancer Network : JNCCN · 2019Pooled it
- Patient and Caregiver Reported Barriers to Cancer Clinical Trial Participation: A Scoping Review.Cancer reports (Hoboken, N.J.) · 2026Article
- Understanding recruitment challenges in Swiss oncology trials: Patient voices from focus groups.Contemporary clinical trials communications · 2026Article
- Impact of Financial Toxicity on Treatment Adherence and Quality of Life in Pancreatic Cancer.JCO oncology practice · 2025Article
- A Web-Based Training Intervention for Primary Care Providers on Preparing Patients for Cancer Treatment Decisions and Conversations About Clinical Trials: Evaluation of a Pilot Study Using Mixed Methods and Follow-Up.JMIR medical education · 2025Article
- Article
- Beyond Barriers: Achieving True Equity in Cancer Care.Current oncology (Toronto, Ont.) · 2025Review
- The DISCO App: A pilot test of a multi-level intervention to reduce the financial burden of cancer through improved cost communication.PEC innovation · 2022Article
- Underutilization of Guideline-Recommended Mismatch Repair/Microsatellite Instability Biomarker Testing in Advanced Colorectal Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Article
- Patient Experience in Clinical Trials: Quality of Life, Financial Burden, and Perception of Care in Patients With Multiple Myeloma or Lymphoma Enrolled on Clinical Trials Compared With Standard Care.JCO oncology practice · 2022Article
- How Do You DISCO? Leveraging the Discussions of Cost App to Reduce Financial Toxicity and Improve Treatment Cost Communication.Oncology issues · 2022Article
- Overcoming Barriers to Clinical Trial Participation: Outcomes of a National Clinical Trial Matching and Navigation Service for Patients With a Blood Cancer.JCO oncology practice · 2021Article
- Article
- Effect of Clinical Trial Participation on Costs to Payers in Metastatic Non-Small-Cell Lung Cancer.JCO oncology practice · 2021Article
- Patient-Reported Out-of-Pocket Costs and Financial Toxicity During Early-Phase Oncology Clinical Trials.The oncologist · 2021Article
- Randomized trial of a web-based nurse education intervention to increase discussion of clinical trials.Contemporary clinical trials communications · 2021Article
- Fair payment and just benefits to enhance diversity in clinical research.Journal of clinical and translational science · 2021Article
- A comparison of patients with acute myeloid leukemia and high-risk myelodysplastic syndrome treated on versus off study.Leukemia & lymphoma · 2019Article
- Article
- Addressing Patients' Priorities as a Strategy to Improve Value.The oncologist · 2016Article
Corrections and comments
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Authors and funding
20 authors.
Yu-Ning WongYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA. yu-ning.wong@fccc.edu.
Mark D SchluchterYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Terrance L AlbrechtYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Al Bowen BensonYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Joanne BuzagloYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Michael CollinsYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Anne Lederman FlammYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Linda FleisherYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Michael KatzYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Tyler G KinzyYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Tasnuva M LiuYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Sharon ManneYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Seunghee MargeviciusYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Dawn M MillerYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Suzanne M MillerYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
David PooleYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Stephanie RaivitchYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Nancy RoachYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Eric RossYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Neal J MeropolYu-Ning Wong, Michael Collins, Suzanne M. Miller, Stephanie Raivitch, and Eric Ross, Fox Chase Cancer Center, Temple University Health System; Joanne Buzaglo, Cancer Support Community Research and Training Institute; Linda Fleisher, Children's Hospital of Philadelphia; David Poole, University of Pennsylvania, Philadelphia, PA; Mark D. Schluchter, Tyler G. Kinzy, Tasnuva M. Liu, Seunghee Margevicius, Dawn M. Miller and Neal J. Meropol, Case Comprehensive Cancer Center, Case Western Reserve University; Neal J. Meropol, University Hospitals Case Medical Center, Seidman Cancer Center; Anne Lederman Flamm, Cleveland Clinic Foundation, Cleveland, OH; Terrance L. Albrecht, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Al Bowen Benson III, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL; Michael Katz,† International Myeloma Foundation, North Hollywood, CA; Sharon Manne, Cancer Institute of New Jersey, New Brunswick, NJ; and Nancy Roach, Fight Colorectal Cancer, Alexandria, VA.
Funding
Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9MTUMOR METABOLISM PROGRAMP30CA043703 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI MARK R CHANCE · 1987 to 2026
$142.3MWORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Margaret von Mehren · 1985 to 2026
$138.8MPreparatory Aid to Improve Decision Making about Cancer Clinical TrialsR01CA127655 · NCI · FOX CHASE CANCER CENTER · PI MEROPOL, NEAL J. · 2008 to 2013
$2.8MNCI NIH HHS P30 CA006927NCI NIH HHS P30 CA043703NCI NIH HHS P30 CA060553NCI NIH HHS P30 CA06927NCI NIH HHS P30 CA43703NCI NIH HHS R01 CA127655
Abstract
purposeThe decision to enroll in a clinical trial is complex given the uncertain risks and benefits of new approaches. Many patients also have financial concerns. We sought to characterize the association between financial concerns and the quality of decision making about clinical trials.
methodsWe conducted a secondary data analysis of a randomized trial of a Web-based educational tool (Preparatory Education About Clinical Trials) designed to improve the preparation of patients with cancer for making decisions about clinical trial enrollment. Patients completed a baseline questionnaire that included three questions related to financial concerns (five-point Likert scales): "How much of a burden on you is the cost of your medical care?," "I'm afraid that my health insurance won't pay for a clinical trial," and "I'm worried that I wouldn't be able to afford the costs of treatment on a clinical trial." Results were summed, with higher scores indicating greater concerns. We used multiple linear regressions to measure the association between concerns and self-reported measures of self-efficacy, preparation for decision making, distress, and decisional conflict in separate models, controlling for sociodemographic characteristics.
resultsOne thousand two hundred eleven patients completed at least one financial concern question. Of these, 27% were 65 years or older, 58% were female, and 24% had a high school education or less. Greater financial concern was associated with lower self-efficacy and preparation for decision making, as well as with greater decisional conflict and distress, even after adjustment for age, race, sex, education, employment, and hospital location (P < .001 for all models).
conclusionFinancial concerns are associated with several psychological constructs that may negatively influence decision quality regarding clinical trials. Greater attention to patients' financial needs and concerns may reduce distress and improve patient decision making.
Indexed as
Decision Support TechniquesAgedClinical Trials as TopicConflict, PsychologicalDecision MakingFemaleHealth Knowledge, Attitudes, PracticeHumansMaleNeoplasmsPatient Education as TopicPatient ParticipationSelf EfficacySurveys and Questionnaires
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