Evidence map›Paper›PMID 26699121›Full record

ArticleEuropean journal of medical research2015

Visualization of stress fractures of the foot using PET-MRI: a feasibility study.

Moritz Crönlein, Isabel Rauscher, Ambros J Beer, Markus Schwaiger, Christoph Schäffeler, Marc Beirer, Stephan Huber, Gunther H Sandmann, Peter Biberthaler, Matthias Eiber and 1 more

Open access · goldAbstract read
In one paragraph

Article in European journal of medical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. PET-MRI for the Study of Metabolic Bone Disease.Current osteoporosis reports · 2018
    Review
  3. Applications of PET-MRI in musculoskeletal disease.Journal of magnetic resonance imaging : JMRI · 2018
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Moritz CrönleinDepartment of Trauma Surgery, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany. moritz.croenlein@mri.tum.de.
Isabel RauscherDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany. isabel.rauscher@tum.de.
Ambros J BeerDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany. Ambros.Beer@uniklinik-ulm.de.
Markus SchwaigerDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany. markus.schwaiger@tum.de.
Christoph SchäffelerMusculoskeletal Imaging Department of Radiology, Kantonsspital Graubünden, Loëstrasse 170, 7000, Chur, Switzerland. schaeffeler@me.com.
Marc BeirerDepartment of Trauma Surgery, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany. marc.beirer@mri.tum.de.
Stephan HuberDepartment of Trauma Surgery, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany. stephan.huber@mri.tum.de.
Gunther H SandmannDepartment of Trauma Surgery, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany. g_sandmann@hotmail.com.
Peter BiberthalerDepartment of Trauma Surgery, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany. peter.biberthaler@mri.tum.de.
Matthias EiberDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany. matthias.eiber@tum.de.
Chlodwig KirchhoffDepartment of Trauma Surgery, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Strasse 22, 81675, Munich, Germany. chlodwig.kirchhoff@mri.tum.de.
Technical University of Munich · DEKlinikum rechts der Isar · DEKantonsspital Graubünden · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiagnosis and treatment of stress fractures still remains to be a clinical and radiological challenge. Therapeutic options vary from conservative treatment to surgical treatment without a clear treatment concept. Recently the combination of PET and MRI has been introduced, aiming a superior diagnostic accuracy in clinical practice. Therefore the aim of our study was to analyse whether PET-MRI would be a feasible technique to recognize stress fractures of the foot and to analyse if our conservative treatment plan leads to a good clinical outcome.

methodsTherefore, 20 patients with suspected stress fractures of the foot and ankle underwent plain radiography and (18)F-Fluoride PET-MRI. Two blinded readers assessed in consensus both imaging techniques for the presence of stress fracture, stress reaction or osteoarthritis. Patients with stress fractures or stress reactions in the foot and ankle area underwent our conservative treatment plan, with immobilization in a VACO®ped cast for 6 weeks under partial weight bearing on forearm crutches. The benefit of our conservative therapeutic concept was evaluated by the patients on the basis of VAS and FAOS scoring systems before and after treatment.

results8 out of 20 patients underwent conservative treatment after diagnosis of either a stress fracture or a stress reaction of the foot and ankle area. PET-MRI identified four stress fractures and seven stress reactions. In all cases, no pathological findings were present on plain X-ray. FAOS and VAS significantly improved according to the patients' records.

conclusionsPET-MRI seems to be a useful modality to diagnose stress fractures and stress reactions of the foot and ankle area, especially when conventional modalities, such as plain radiographs fail. Conservative management is a promising therapeutic option for the treatment of stress fractures. To rule out the benefits compared to a surgical treatment plan, further studies are needed.

Indexed as

AdultAgedFeasibility StudiesFemaleFluorine RadioisotopesFoot InjuriesFractures, BoneFractures, StressHumansMagnetic Resonance ImagingMaleMiddle AgedPositron-Emission TomographyYoung AdultFluorine Radioisotopes

Identifiers

PMID26699121
PMCPMC4690332
OpenAlexW2215307571

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.