ArticleEuropean journal of obstetrics, gynecology, and reproductive biology2016
Incidence of occult leiomyosarcoma in presumed morcellation cases: a database study.
Article in European journal of obstetrics, gynecology, and reproductive biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 50 citations in OpenAlex.
- Advances and Challenges in Minimally Invasive Myomectomy: A Narrative Review.Journal of clinical medicine · 2025Review
- Clinico-radio-histopathological Correlation of Leiomyoma Variant, STUMP, and Sarcoma: A Retrospective Study.Oman medical journal · 2025Article
- MMP14 expression and collagen remodelling support uterine leiomyosarcoma aggressiveness.Molecular oncology · 2024Article
- Article
- A differential diagnosis between uterine leiomyoma and leiomyosarcoma using transcriptome analysis.BMC cancer · 2023Article
- Preoperative Differentiation of Uterine Leiomyomas and Leiomyosarcomas: Current Possibilities and Future Directions.Cancers · 2022Review
- Safety Warning about Laparoscopic Power Morcellation in Hysterectomy: A Cost-Effectiveness Analysis of National Impact.Women's health reports (New Rochelle, N.Y.) · 2022Article
- Prevalence and occult rates of uterine leiomyosarcoma.Medicine · 2020Observational
- Morcellation of the Uterus: Is There Any Place?Current oncology reports · 2020Review
- Association Between Power Morcellation and Mortality in Women With Unexpected Uterine Cancer Undergoing Hysterectomy or Myomectomy.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2019Article
- Prevalence, characteristics, and risk factors of occult uterine cancer in presumed benign hysterectomy.American journal of obstetrics and gynecology · 2019Article
- Incidence and groups at risk for unexpected uterine leiomyosarcoma: a Dutch nationwide cohort study.Archives of gynecology and obstetrics · 2019Article
- The Impact of Varying Numbers of Quadrivalent Human Papillomavirus Vaccine Doses on Anogenital Warts in the United States: A Database Study.Journal of lower genital tract disease · 2018Article
- Malignant transformation of uterine leiomyoma to myxoid leiomyosarcoma after morcellation associated withOncotarget · 2018Article
- Outcomes of robotic, laparoscopic, and open hysterectomy for benign conditions in obese patientsJournal of the Turkish German Gynecological Association · 2018Article
- Comment on "Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation".Reproductive biology and endocrinology : RB&E · 2017Article
- Laparoscopic hysterectomy with morcellation vs abdominal hysterectomy for presumed fibroids: an updated decision analysis following the 2014 Food and Drug Administration safety communications.American journal of obstetrics and gynecology · 2017Article
- Is Laparoscopic Power Morcellation of Fibroids a Cardinal Sin in 2017?Journal of obstetrics and gynaecology of India · 2017Article
- Survey among ESGE members on leiomyosarcoma morcellation incidence.Gynecological surgery · 2017Article
- Uterine sarcoma - current perspectives.International journal of women's health · 2017Review
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveOur objective was to estimate the incidence of uterine leiomyosarcoma in patients with leiomyomas following laparoscopic supracervical hysterectomy and myomectomy procedures. STUDY
designFor this study, we analyzed records of 13,964 women aged 25-64 years who underwent laparoscopic supracervical hysterectomies or myomectomies for leiomyomas from 2002 to 2011 using Clinformatics DataMart. Patient records were divided into two groups: history of laparoscopic supracervical hysterectomy and history of myomectomy. Subjects were tracked to identify diagnosis of leiomyosarcoma within 1 year of the procedure. We analyzed data from the 25-39, 40-49, and 50-64 age brackets. Evidence was obtained from a cohort study from national private insurance claims in the US.
resultsOur results showed the incidence of occult leiomyosarcoma developing within 1 year following supracervical hysterectomy using a laparoscopic-assisted approach are 9.8, 10.7, and 33.4 per 10,000 for the 25-39, 40-49, and 50-64 age brackets, respectively; the overall incidence rate is 13.1 per 10,000. The incidence rate of occult leiomyosarcoma developing within 1 year following myomectomy using a laparoscopic-assisted approach are 0.0, 33.8, and 90.1 per 10,000 for the 25-39, 40-49, and 50-64 age brackets, respectively; the overall incidence rate is 17.3 per 10,000.
conclusionOur analysis shows the overall risk of being diagnosed with occult leiomyosarcoma is 12.9 per 10,000 in laparoscopic-assisted supracervical hysterectomy and myomectomy for patients younger than 49. There is no evidence of occult leiomyosarcoma 1 year after operation for patients younger than 40 who underwent laparoscopic myomectomy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.