Evidence map›Paper›PMID 26698113›Full record

ArticleBiomedical engineering online2015

Left ventricular ejection fraction estimation using mutual information on technetium-99m multiple-gated SPECT scans.

Shih-Neng Yang, Shung-Shung Sun, Geoffrey Zhang, Kuei-Ting Chou, Shih-Wen Lo, Yu-Rou Chiou, Fang-Jing Li, Tzung-Chi Huang

Abstract read
In one paragraph

Article in Biomedical engineering online, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. The role of multimodality imaging in HIV-related heart disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  4. Nuclear cardiology in China: 2017.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shih-Neng YangDepartment of Biomedical Imaging and Radiological Science, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan. shineng.yang@msa.hinet.net.
Shung-Shung SunDepartment of Nuclear Medicine and PET Center, China Medical University Hospital, No. 2, Yude Road, Taichung, 40447, Taiwan. sunss0715@yahoo.com.tw.
Geoffrey ZhangDepartment of Radiation Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL, 33612, USA. Geoffrey.Zhang@moffitt.org.
Kuei-Ting ChouDepartment of Biomedical Imaging and Radiological Science, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan. a20045111@hotmail.com.
Shih-Wen LoDepartment of Radiology, Taipei Municipal Wanfang Hospital, No.111, Section 3, Hsing-Long Rd, Taipei, 116, Taiwan. dark5532@hotmail.com.tw.
Yu-Rou ChiouDepartment of Biomedical Imaging and Radiological Science, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan. yu-rou0818@hotmail.com.tw.
Fang-Jing LiDepartment of Radiation Oncology, Tri-Service General Hospital, No. 325, Section 2, Chenggong Rd., Neihu District, Taipei City, 114, Taiwan. judy19805846@gmail.com.
Tzung-Chi HuangDepartment of Biomedical Imaging and Radiological Science, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan. tzungchi.huang@mail.cmu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA new non-linear approach was applied to calculate the left ventricular ejection fraction (LVEF) using multigated acquisition (MUGA) images.

methodsIn this study, 50 patients originally for the estimation of the percentage of LVEF to monitor the effects of various cardiotoxic drugs in chemotherapy were retrospectively selected. All patients had both MUGA and echocardiography examinations (ECHO LVEF) at the same time. Mutual information (MI) theory was utilized to calculate the LVEF using MUGA imaging (MUGA MI).

resultsMUGA MI estimation was significantly different from MUGA LVEF and ECHO LVEF, respectively (p < 0.005). The higher repeatability for MUGA MI can be observed in the figure by the higher correlation coefficient for MUGA MI (r = 0.95) compared with that of MUGA LVEF (r = 0.80). Again, the reproducibility was better for MUGA MI (r = 0.90, 0.92) than MUGA LVEF (r = 0.77, 0.83). The higher correlation coefficients were obtained between proposed MUGA MI and ECHO LVEF compared to that between the conventional MUGA LVEF and ECHO LVEF.

conclusionsMUGA image with the aid of MI is promising to be more interchangeable LVEF to ECHO LVEF measurement as compared with the conventional approach on MUGA image.

Indexed as

Cardiac-Gated Single-Photon Emission Computer-Assisted TomographyImage Processing, Computer-AssistedTechnetiumVentricular Function, LeftAdultAgedAged, 80 and overCardiotoxinsFemaleHumansMaleMiddle AgedRetrospective StudiesCardiotoxinsTechnetium

Identifiers

PMID26698113
PMCPMC4690273

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.