Evidence map›Paper›PMID 26697984›Full record

ArticleAmerican journal of physiology. Renal physiology2016

Evidence for a mitochondrial angiotensin-(1-7) system in the kidney.

Bryan A Wilson, Manisha Nautiyal, TanYa M Gwathmey, James C Rose, Mark C Chappell

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

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  11. Mitochondrial angiotensin receptors and cardioprotective pathways.American journal of physiology. Heart and circulatory physiology · 2019
    Review
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  15. Luminal ANG II is internalized as a complex with ATAmerican journal of physiology. Renal physiology · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bryan A WilsonHypertension and Vascular Research Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Manisha NautiyalDivision of Endocrinology, Diabetes, and Metabolism, University of Florida, Gainesville, Florida.
TanYa M GwathmeyHypertension and Vascular Research Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
James C RoseDepartment of Obstetrics and Gynecology, Wake Forest University School of Medicine, Winston-Salem, North Carolina; and.
Mark C ChappellHypertension and Vascular Research Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina; mchappel@wakehealth.edu.
Wake Forest University · USUniversity of Florida · US

Funding

The Impact of Antenatal Steroid Exposure on the Intrarenal Renin-Angiotensin SystP01HD047584 · NICHD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ROSE, JAMES C. · 2005 to 2016
$13.0M
Integrative Lipid Metabolism, Inflammation, and Chronic DiseasesT32HL091797 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PARKS, JOHN S · 2008 to 2017
$1.8M
Novel Angiotensin-(1-7) Endopeptidase in Fetal ProgrammingR21HD084227 · NICHD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHAPPELL, MARK C, ROSE, JAMES C. · 2016 to 2017
$426k
NHLBI NIH HHS T32 HL091797NICHD NIH HHS P01 HD047584NICHD NIH HHS R21 HD084227
6 · The paper itself

Abstract

Evidence for an intracellular renin-angiotensin system (RAS) in various cell organelles now includes the endoplasmic reticulum, nucleus, and mitochondria (Mito). Indeed, angiotensin (ANG) AT

Indexed as

Angiotensin IAngiotensinogenAnimalsFemaleKidneyMitochondriaPeptide FragmentsReninRenin-Angiotensin SystemSheepAngiotensin Iangiotensin I (1-7)AngiotensinogenPeptide FragmentsReninANG-(1–7)angiotensin-(1–7)kidneymitochondriarenin-angiotensin system

Identifiers

PMID26697984
PMCPMC4824145
OpenAlexW2287883668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.