Evidence map›Paper›PMID 26697437›Full record

ArticleFrontiers in veterinary science2015

Long-Term Dynamics of Coxiella burnetii in Farmed Red Deer (Cervus elaphus).

David González-Barrio, Isabel G Fernández-de-Mera, José Antonio Ortiz, João Queirós, Francisco Ruiz-Fons

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Seropositivity forPathogens (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Article
  7. Frontiers in veterinary science · 2022
    Review
  8. Prevalence ofEpidemiology and infection · 2021
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

David González-BarrioHealth and Biotechnology (SaBio) Group, Spanish Wildlife Research Institute IREC (CSIC, Universidad de Castilla-La Mancha, Junta de Comunidades de Castilla-La Mancha) , Ciudad Real , Spain.
Isabel G Fernández-de-MeraHealth and Biotechnology (SaBio) Group, Spanish Wildlife Research Institute IREC (CSIC, Universidad de Castilla-La Mancha, Junta de Comunidades de Castilla-La Mancha) , Ciudad Real , Spain.
José Antonio OrtizMedianilla S. A. , Benalup-Casas Viejas , Spain.
João QueirósHealth and Biotechnology (SaBio) Group, Spanish Wildlife Research Institute IREC (CSIC, Universidad de Castilla-La Mancha, Junta de Comunidades de Castilla-La Mancha) , Ciudad Real , Spain ; Centro de Investigacão em Biodiversidade e Recursos Genéticos (CIBIO), InBio Laboratório Associado, Universidade do Porto , Vairão , Portugal ; Departamento de Biologia, Faculdade de Ciências da Universidade do Porto , Porto , Portugal.
Francisco Ruiz-FonsHealth and Biotechnology (SaBio) Group, Spanish Wildlife Research Institute IREC (CSIC, Universidad de Castilla-La Mancha, Junta de Comunidades de Castilla-La Mancha) , Ciudad Real , Spain.
Regional Government of Castile-La Mancha · ESUniversity of Castilla-La Mancha · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several aspects of the dynamics of Coxiella burnetii that are relevant for the implementation of control strategies in ruminant herds with endemic Q fever are unknown. We designed a longitudinal study to monitor the dynamics of exposure to C. burnetii in a red deer herd with endemic infection in order to allow the design of Q fever-specific control approaches. Other relevant aspects of the dynamics of C. burnetii - the effect of herd immune status, age, season, and early infection on exposure, the average half-life of antibodies, the presence and duration of maternal humoral immunity, and the age of first exposure - were analyzed. The dynamics of C. burnetii in deer herds seems to be modulated by host herd and host individual factors and by particular host life-history traits. Red deer females become exposed to C. burnetii at the beginning of their second year since maternal antibodies protect them after birth and during the main pathogen shedding season - at the end of spring-early summer. Infection pressure varies between years, probably associated with herd immunity effects, determining inter-annual variation in the risk of exposure. These results suggest that any strategy applied to control C. burnetii in deer herds should be designed to induce immunity in their first year of life immediately after losing maternal antibodies. The short average life of C. burnetii antibodies suggests that any protection based on humoral immunity would require re-vaccination every 6 months.

Indexed as

controlepidemiologyQ feverwildlifezoonosis

Identifiers

PMID26697437
PMCPMC4676194
OpenAlexW2203152085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.