ArticleGenomics data2015
Transcriptional changes in sensory ganglia associated with primary afferent axon collateral sprouting in spared dermatome model.
Article in Genomics data, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- A time-resolved RNA-sequencing dataset of transcriptional responses in PC12 cells to NGF withdrawal and replenishment.Data in brief · 2026Article
- Tissue damage-induced axon injury-associated responses in sensory neurons: requirements, prevention, and potential role in persistent post-surgical pain.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Skin Reinnervation by Collateral Sprouting Following Spared Nerve Injury in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Swallowing dysfunction following radiation to the rat mylohyoid muscle is associated with sensory neuron injury.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Altered expression of itch‑related mediators in the lower cervical spinal cord in mouse models of two types of chronic itch.International journal of molecular medicine · 2019Article
- Transcriptome of dorsal root ganglia caudal to a spinal cord injury with modulated behavioral activity.Scientific data · 2019Article
- Identification of lncRNA and mRNA expression profiles in rat spinal cords at various time‑points following cardiac ischemia/reperfusion.International journal of molecular medicine · 2019Article
- Framework for reanalysis of publicly available Affymetrix® GeneChip® data sets based on functional regions of interest.BMC genomics · 2017Article
- Altered expression of target genes of spinal cord in different itch models compared with capsaicin assessed by RT-qPCR validation.Oncotarget · 2017Article
- The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
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Authors and funding
12 authors at 7 institutions in 2 countries.
Funding
Abstract
Primary afferent collateral sprouting is a process whereby non-injured primary afferent neurons respond to some stimulus and extend new branches from existing axons. Neurons of both the central and peripheral nervous systems undergo this process, which contributes to both adaptive and maladaptive plasticity (e.g., [1], [2], [3], [4], [5], [6], [7], [8], [9]). In the model used here (the "spared dermatome" model), the intact sensory neurons respond to the denervation of adjacent areas of skin by sprouting new axon branches into that adjacent denervated territory. Investigations of gene expression changes associated with collateral sprouting can provide a better understanding of the molecular mechanisms controlling this process. Consequently, it can be used to develop treatments to promote functional recovery for spinal cord injury and other similar conditions. This report includes raw gene expression data files from microarray experiments in order to study the gene regulation in spared sensory ganglia in the initiation (7 days) and maintenance (14 days) phases of the spared dermatome model relative to intact ("naïve") sensory ganglia. Data has been deposited into GEO (GSE72551).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.