Evidence map›Paper›PMID 26697245›Full record

ArticleCase reports in neurological medicine2015

Culture Negative Listeria monocytogenes Meningitis Resulting in Hydrocephalus and Severe Neurological Sequelae in a Previously Healthy Immunocompetent Man with Penicillin Allergy.

Shahin Gaini, Gunn Hege Karlsen, Anirban Nandy, Heidi Madsen, Debes Hammershaimb Christiansen, Sanna Á Borg

Open access · goldAbstract read
In one paragraph

Article in Case reports in neurological medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Clinical Presentations and Nosocomial Infections of Neurolisteriosis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Review
  2. Plasma-Treated Water AffectsFrontiers in microbiology · 2021
    Article
  3. A case ofIDCases · 2020
    Article
  4. Rhombencephalitis caused byWorld journal of clinical cases · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Shahin GainiMedical Department, Infectious Diseases Division, National Hospital of the Faroe Islands, 100 Tórshavn, Faroe Islands ; Infectious Diseases Research Unit, Odense University Hospital and University of Southern Denmark, 5000 Odense, Denmark ; Department of Science and Technology, University of the Faroe Islands, 100 Tórshavn, Faroe Islands.
Gunn Hege KarlsenMedical Department, Infectious Diseases Division, National Hospital of the Faroe Islands, 100 Tórshavn, Faroe Islands.
Anirban NandyMedical Department, Infectious Diseases Division, National Hospital of the Faroe Islands, 100 Tórshavn, Faroe Islands.
Heidi MadsenMedical Department, Infectious Diseases Division, National Hospital of the Faroe Islands, 100 Tórshavn, Faroe Islands.
Debes Hammershaimb ChristiansenNational Reference Laboratory for Fish and Animal Diseases, Faroese Food Security Agency, 100 Tórshavn, Faroe Islands.
Sanna Á BorgMedical Department, Infectious Diseases Division, National Hospital of the Faroe Islands, 100 Tórshavn, Faroe Islands.
University of the Faroe Islands · FOFaroese Research Council · FOOdense University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A previously healthy 74-year-old Caucasian man with penicillin allergy was admitted with evolving headache, confusion, fever, and neck stiffness. Treatment for bacterial meningitis with dexamethasone and monotherapy ceftriaxone was started. The cerebrospinal fluid showed negative microscopy for bacteria, no bacterial growth, and negative polymerase chain reaction for bacterial DNA. The patient developed hydrocephalus on a second CT scan of the brain on the 5th day of admission. An external ventricular catheter was inserted and Listeria monocytogenes grew in the cerebrospinal fluid from the catheter. The patient had severe neurological sequelae. This case report emphasises the importance of covering empirically for Listeria monocytogenes in all patients with penicillin allergy with suspected bacterial meningitis. The case also shows that it is possible to have significant infection and inflammation even with negative microscopy, negative cultures, and negative broad range polymerase chain reaction in cases of Listeria meningitis. Follow-up spinal taps can be necessary to detect the presence of Listeria monocytogenes.

Identifiers

PMID26697245
PMCPMC4678059
OpenAlexW2194656940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.