Evidence map›Paper›PMID 26697118›Full record

ArticleDiabetology & metabolic syndrome2015

New digital tool to facilitate subcutaneous insulin therapy orders: an inpatient insulin dose calculator.

Marcos Tadashi Kakitani Toyoshima, Alexandre Barbosa Câmara de Souza, Sharon Nina Admoni, Priscilla Cukier, Simão Augusto Lottenberg, Ana Claudia Latronico, Márcia Nery

Open access · goldAbstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Arquivos brasileiros de cardiologia · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marcos Tadashi Kakitani ToyoshimaServiço de Endocrinologia e Metabologia do Hospital das Clínicas da Faculdade de Medicina da, Universidade de São Paulo, Av. Dr. Enéas Carvalho de Aguiar, 255-7º andar, Sala 7037, São Paulo, SP CEP: 05403-900 Brazil ; Unidade de Oncologia Endócrina do Instituto do Câncer do Estado de São Paulo-Hospital das Clínicas da Faculdade de Medicina da, Universidade de São Paulo, Av. Dr. Arnaldo, 251-5º andar, São Paulo, SP CEP: 01255-000 Brazil ; Centro de Medicina Preventiva, Hospital Israelita Albert Einstein, Av. Brasil, 953, São Paulo, SP CEP: 01431-000 Brazil.ORCID 0000-0002-9146-4606
Alexandre Barbosa Câmara de SouzaServiço de Endocrinologia e Metabologia do Hospital das Clínicas da Faculdade de Medicina da, Universidade de São Paulo, Av. Dr. Enéas Carvalho de Aguiar, 255-7º andar, Sala 7037, São Paulo, SP CEP: 05403-900 Brazil.
Sharon Nina AdmoniServiço de Endocrinologia e Metabologia do Hospital das Clínicas da Faculdade de Medicina da, Universidade de São Paulo, Av. Dr. Enéas Carvalho de Aguiar, 255-7º andar, Sala 7037, São Paulo, SP CEP: 05403-900 Brazil.
Priscilla CukierServiço de Endocrinologia e Metabologia do Hospital das Clínicas da Faculdade de Medicina da, Universidade de São Paulo, Av. Dr. Enéas Carvalho de Aguiar, 255-7º andar, Sala 7037, São Paulo, SP CEP: 05403-900 Brazil ; Unidade de Oncologia Endócrina do Instituto do Câncer do Estado de São Paulo-Hospital das Clínicas da Faculdade de Medicina da, Universidade de São Paulo, Av. Dr. Arnaldo, 251-5º andar, São Paulo, SP CEP: 01255-000 Brazil.
Simão Augusto LottenbergServiço de Endocrinologia e Metabologia do Hospital das Clínicas da Faculdade de Medicina da, Universidade de São Paulo, Av. Dr. Enéas Carvalho de Aguiar, 255-7º andar, Sala 7037, São Paulo, SP CEP: 05403-900 Brazil.
Ana Claudia LatronicoServiço de Endocrinologia e Metabologia do Hospital das Clínicas da Faculdade de Medicina da, Universidade de São Paulo, Av. Dr. Enéas Carvalho de Aguiar, 255-7º andar, Sala 7037, São Paulo, SP CEP: 05403-900 Brazil.
Márcia NeryServiço de Endocrinologia e Metabologia do Hospital das Clínicas da Faculdade de Medicina da, Universidade de São Paulo, Av. Dr. Enéas Carvalho de Aguiar, 255-7º andar, Sala 7037, São Paulo, SP CEP: 05403-900 Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInpatient hyperglycemia is associated with adverse outcomes in hospitalized patients, with or without known diabetes. The adherence to American College of Endocrinology and American Diabetes Association guidelines recommendations for inpatient glycemic control is still poor, probably because of their complexity and fear of hypoglycemia.

objectiveTo create software system that can assist health care providers and hospitalists to manage the insulin therapy orders and turn them into a less complicated issue.

methodsA software system was idealized and developed, according to recommendations of major consensus and medical literature.

resultsHTML software was developed to be readily accessed from a workstation, tablet or smartphone. Standard initial daily total dose of insulin was 0.4 units/kg and could be modified by distinct factors, such as chronological age, renal and liver function, and high dose corticosteroids use. Insulin therapy consisted of basal, prandial and correction insulin according to nutritional support, glycemic control and outpatient treatment for diabetes. Human insulin or insulin analogues could be options for insulin therapy. Sensitivity factor was based on 1800 Rule for rapid-acting insulin and the 1500 Rule for short-acting insulin. Insulin-naïve patients with initial BG level less than 250 mg/dL were considered to have an initial step-wise approach with prandial and correction insulin. The calculator system has allowed insulin dose readjustments periodically, according to daily average blood glucose measurements.

conclusionWe developed software that can be a useful tool for all public hospitals, where generally human insulin is the only available.

Indexed as

Diabetes mellitusHospitalizationHyperglycemiaInsulin

Identifiers

PMID26697118
PMCPMC4687348
OpenAlexW2202647275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.