ArticleFrontiers in microbiology2015
Single-Cell Analysis of Growth and Cell Division of the Anaerobe Desulfovibrio vulgaris Hildenborough.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 38 citations in OpenAlex.
- Microbial single-cell applications under anoxic conditions.Applied and environmental microbiology · 2024Review
- Impact of Graphene Layers on Genetic Expression and Regulation within Sulfate-Reducing Biofilms.Microorganisms · 2024Article
- Bioinformatic Assessment of Factors Affecting the Correlation between Protein Abundance and Elongation Efficiency in Prokaryotes.International journal of molecular sciences · 2022Article
- Inhibition of Sulfate Reduction and Cell Division by Desulfovibrio desulfuricans Coated in Palladium Metal.Applied and environmental microbiology · 2022Article
- OrpR is a σMolecular microbiology · 2021Article
- Bacterial cell proliferation: from molecules to cells.FEMS microbiology reviews · 2021Review
- Modeling homeostasis mechanisms that set the target cell size.Scientific reports · 2020Article
- The bacterial MrpScientific reports · 2019Article
- Effect of Blastocystis sp. in dengue patients-Increase in the treatment cost and exacerbation of symptoms.PloS one · 2019Article
- Cell size control and gene expression homeostasis in single-cells.Current opinion in systems biology · 2018Article
- Archaeal cells share common size control with bacteria despite noisier growth and division.Nature microbiology · 2018Article
- In vitro and in vivo thermal stress induces proliferation of Blastocystis sp.Parasitology research · 2018Article
- Beyond the bulk: disclosing the life of single microbial cells.FEMS microbiology reviews · 2017Review
- Sizing up the bacterial cell cycle.Nature reviews. Microbiology · 2017Review
- Analysis of Noise Mechanisms in Cell-Size Control.Biophysical journal · 2017Article
- Details Matter: Noise and Model Structure Set the Relationship between Cell Size and Cell Cycle Timing.Frontiers in cell and developmental biology · 2017Article
- A mechanistic stochastic framework for regulating bacterial cell division.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent years have seen significant progress in understanding basic bacterial cell cycle properties such as cell growth and cell division. While characterization and regulation of bacterial cell cycle is quite well-documented in the case of fast growing aerobic model organisms, no data has been so far reported for anaerobic bacteria. This lack of information in anaerobic microorganisms can mainly be explained by the absence of molecular and cellular tools such as single cell microscopy and fluorescent probes usable for anaerobes and essential to study cellular events and/or subcellular localization of the actors involved in cell cycle. In this study, single-cell microscopy has been adapted to study for the first time, in real time, the cell cycle of a bacterial anaerobe, Desulfovibrio vulgaris Hildenborough (DvH). This single-cell analysis provides mechanistic insights into the cell division cycle of DvH, which seems to be governed by the recently discussed so-called incremental model that generates remarkably homogeneous cell sizes. Furthermore, cell division was reversibly blocked during oxygen exposure. This may constitute a strategy for anaerobic cells to cope with transient exposure to oxygen that they may encounter in their natural environment, thereby contributing to their aerotolerance. This study lays the foundation for the first molecular, single-cell assay that will address factors that cannot otherwise be resolved in bulk assays and that will allow visualization of a wide range of molecular mechanisms within living anaerobic cells.
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