Evidence map›Paper›PMID 26696793›Full record

ArticleMicrofluidics and nanofluidics2015

Deformation of a single mouse oocyte in a constricted microfluidic channel.

ZhengYuan Luo, Sinan Guven, Irep Gozen, Pu Chen, Savas Tasoglu, Raymond M Anchan, BoFeng Bai, Utkan Demirci

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microfluidics and nanofluidics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. TiACS omega · 2026
    Article
  3. From Cytoskeletal Remodeling to Oocyte Quality: The Emerging Role of Mechanics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Design and Use of a Microfluidic Device for Oocyte Quality Screening.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  9. Article
  10. Single-cell Technology in Stem Cell Research.Current stem cell research & therapy · 2025
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Glioma-on-a-Chip Models.Micromachines · 2021
    Article
  17. Hemp-Based Microfluidics.Micromachines · 2021
    Article
  18. Article
  19. Hydrodynamics in Cell Studies.Chemical reviews · 2018
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

ZhengYuan LuoDivision of Biomedical Engineering, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, MA, 02139, USA ; State Key Laboratory of Multiphase Flow in Power Engineering, Xi'an Jiaotong University, Xi'an 710049, P.R. China.
Sinan GuvenDivision of Biomedical Engineering, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, MA, 02139, USA ; Demirci Bio-Acoustic MEMS in Medicine (BAMM) Lab, Department of Radiology, Stanford University School of Medicine, Canary Center for Early Cancer Detection, Stanford, CA, 94304, USA.
Irep GozenDivision of Biomedical Engineering, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, MA, 02139, USA.
Pu ChenDivision of Biomedical Engineering, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, MA, 02139, USA ; Demirci Bio-Acoustic MEMS in Medicine (BAMM) Lab, Department of Radiology, Stanford University School of Medicine, Canary Center for Early Cancer Detection, Stanford, CA, 94304, USA.
Savas TasogluDivision of Biomedical Engineering, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, MA, 02139, USA.
Raymond M AnchanCenter for Infertility and Reproductive Surgery, Obstetrics Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
BoFeng BaiState Key Laboratory of Multiphase Flow in Power Engineering, Xi'an Jiaotong University, Xi'an 710049, P.R. China.
Utkan DemirciDivision of Biomedical Engineering, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, MA, 02139, USA ; Demirci Bio-Acoustic MEMS in Medicine (BAMM) Lab, Department of Radiology, Stanford University School of Medicine, Canary Center for Early Cancer Detection, Stanford, CA, 94304, USA.

Funding

Minimizing the role of cryoprotectant toxicity for cryopreservationR01EB015776 · NIBIB · STANFORD UNIVERSITY · PI DEMIRCI, UTKAN · 2012 to 2015
$1.5M
NIBIB NIH HHS R01 EB015776
6 · The paper itself

Abstract

Single oocyte manipulation in microfluidic channels via precisely controlled flow is critical in microfluidic-based

Indexed as

microfluidicsOocyte deformationsingle cell trappingspindle damage

Identifiers

PMID26696793
PMCPMC4684828

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.