Evidence map›Paper›PMID 26696776›Full record

ArticleBMC ear, nose, and throat disorders2015

Laryngopharyngeal reflux disease in the Greek general population, prevalence and risk factors.

Nikolaos Spantideas, Eirini Drosou, Anastasia Bougea, Dimitrios Assimakopoulos

Open access · hybridAbstract read
In one paragraph

Article in BMC ear, nose, and throat disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Meta-analysis of Proton Pump Inhibitors in the Treatment of Pharyngeal Reflux Disease.Computational and mathematical methods in medicine · 2022
    Pooled it
  3. Pooled it
  4. Randomized Controlled Trial of Upper Esophageal Sphincter Assist Device in Laryngopharyngeal Reflux Disease.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Trial
  5. Lansoprazole for persistent throat symptoms in secondary care: the TOPPITS RCT.Health technology assessment (Winchester, England) · 2021
    Trial
  6. Global burden of Laryngopharyngeal reflux disease: a systematic review of epidemiology, cost-burden and awareness.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  7. Reducing the Duration of 24-Hour Multichannel Intraluminal Impedance-pH Monitoring for Laryngopharyngeal Reflux.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
  8. Review
  9. Laryngopharyngeal Reflux Prevalence and Predictors Among Doctors.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  10. Bama pig is a suitable animal for studying laryngopharyngeal reflux disease.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025
    Article
  11. Article
  12. Validation of the Laryngeal Cognitive-Affective Tool.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Article
  13. Association between oropharyngeal ph-monitoring, pepsin saliva concentration and degree of apnea-hypopnea index of obstructive sleep apnea.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2023
    Article
  14. Article
  15. Prevalence of Laryngopharyngeal Reflux Disease in Indian Population.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. How I Approach Laryngopharyngoesophageal Reflux (LPR).Current gastroenterology reports · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nikolaos SpantideasAthens Speech Language and Swallowing Institute, 10 Lontou Street, Glyfada, Athens, 16675 Greece.
Eirini DrosouAthens Speech Language and Swallowing Institute, 37 Oinois Street, Glyfada, Athens, 16674 Greece.
Anastasia BougeaAthens Speech and Language Institute, 1 Griva Digeni Street, Agios Dimitrios, Athens, 17342 Greece.
Dimitrios AssimakopoulosDepartment of Otorhinolaryngology, University Hospital of Ioannina, Medical School of Ioannina University, 51 Napoleontos Zerva Street, Ioannina, 45332 Greece.
Institute for Language and Speech Processing · GRUniversity Hospital of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the prevalence of laryngopharyngeal reflux (LPR) in the Greek general population and its risk factors.

methodsQuestionnaire based epidemiological, adult participants' survey. The Reflux Symptom Index (RSI) was used for the assessment of LPR prevalence. The RSI questionnaire was completed by 340 (183 male and 157 female) randomly selected subjects. Subjects with RSI score ≥13 were considered as LPR patients and those with RSI score <13 were considered as non LPR subjects.

resultsThe prevalence of LPR in the general Greek population was found to be 18.8 % with no statistically significant difference between the two genders (p > 0.05). The age group of 50-64 years showed the higher prevalence rate. Tobacco smoking and alcohol consumption were found to be related with LPR. No reported concomitant disease or medication was found to be related with LPR.

conclusionsLPR prevalence in the Greek general population was found to be 18.8 %. Tobacco smoking and alcohol consumption were found to be related with LPR.

Indexed as

Epidemiologic studyGastroesophageal refluxLaryngopharyngeal refluxRefluxRisk factors

Identifiers

PMID26696776
PMCPMC4687326
OpenAlexW2206426110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.