ArticlePloS one2015
A Comparison of the Beneficial Effects of Live and Heat-Inactivated Baker's Yeast on Nile Tilapia: Suggestions on the Role and Function of the Secretory Metabolites Released from the Yeast.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 85 citations in OpenAlex.
- Gut yeasts accelerate chill coma recovery in Drosophila melanogaster.The Journal of experimental biology · 2026Article
- Effects of passion fruit peel (Passiflora edulis) pectin and red yeast (Sporodiobolus pararoseus) cells on growth, immunity, intestinal morphology, gene expression, and gut microbiota in Nile tilapia (Oreochromis niloticus).Scientific reports · 2024Article
- Effect of fatty acid-enriched black soldier fly larvae meal combined with chitinase on the metabolic processes of Nile tilapia.The British journal of nutrition · 2024Article
- Advances in the Effects of Dietary Macronutrients on the Gut Microbiota of Tilapia (Microorganisms · 2024Review
- Effects of Dietary Yeast,Aquaculture nutrition · 2024Article
- A Comparison of the Beneficial Effects of Inorganic, Organic, and Elemental Nano-selenium on Nile Tilapia: Growth, Immunity, Oxidative Status, Gut Morphology, and Immune Gene Expression.Biological trace element research · 2022Article
- The Effect of DietaryLife (Basel, Switzerland) · 2022Article
- Dietary Mannan Oligosaccharides Enhance the Non-Specific Immunity, Intestinal Health, and Resistance Capacity of Juvenile Blunt Snout Bream (Frontiers in immunology · 2022Article
- Probiotics Modulate Tilapia Resistance and Immune Response against Tilapia Lake Virus Infection.Pathogens (Basel, Switzerland) · 2020Article
- Metabarcoding Analyses of Gut Microbiota of Nile Tilapia (Microorganisms · 2020Article
- Effects of dietary probiotic supplementation on the growth, gut health and disease resistance of juvenile Nile tilapia (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2020Article
- Effects of partial replacement of fish meal by yeast hydrolysate on antioxidant capability, intestinal morphology, and inflammation-related gene expression of juvenile Jian carp (Cyprinus carpio var. Jian).Fish physiology and biochemistry · 2019Article
- Bioprocessed poultry by-product meals on growth, gut health and fatty acid synthesis of juvenile barramundi, Lates calcarifer (Bloch).PloS one · 2019Article
- Article
- Yeast culture dietary supplementation modulates gut microbiota, growth and biochemical parameters of grass carp.Microbial biotechnology · 2018Article
- Exposure to Yeast Shapes the Intestinal Bacterial Community Assembly in Zebrafish Larvae.Frontiers in microbiology · 2018Article
- Performance ofJournal of nutrition and metabolism · 2017Article
- Protective Yeasts ControlFrontiers in cellular and infection microbiology · 2016Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Yeast is frequently used as a probiotic in aquaculture with the potential to substitute for antibiotics. In this study, the involvement and extent to which the viability of yeast cells and thus the secretory metabolites released from the yeast contribute to effects of baker's yeast was investigated in Nile tilapia. No yeast, live yeast or heat-inactivated baker's yeast were added to basal diets high in fishmeal and low in soybean (diet A) or low in fishmeal and high in soybean (diet B), which were fed to fish for 8 weeks. Growth, feed utilization, gut microvilli morphology, and expressions of hsp70 and inflammation-related cytokines in the intestine and head kidney were assessed. Intestinal microbiota was investigated using 16S rRNA gene pyrosequencing. Gut alkaline phosphatase (AKP) activity was measured after challenging the fish with Aeromonas hydrophila. Results showed that live yeast significantly improved FBW and WG (P < 0.05), and tended to improve FCR (P = 0.06) of fish compared to the control (no yeast). No significant differences were observed between inactivated yeast and control. Live yeast improved gut microvilli length (P < 0.001) and density (P < 0.05) while inactivated yeast did not. The hsp70 expression level in both the intestine and head kidney of fish was significantly reduced by live yeast (P < 0.05) but not inactivated yeast. Live yeast but not inactivated yeast reduced intestinal expression of tnfα (P < 0.05), tgfβ (P < 0.05 under diet A) and il1β (P = 0.08). Intestinal Lactococcus spp. numbers were enriched by both live and inactivated yeast. Lastly, both live and inactivated yeast reduced the gut AKP activity compared to the control (P < 0.001), indicating protection of the host against infection by A. hydrophila. In conclusion, secretory metabolites did not play major roles in the growth promotion and disease protection effects of yeast. Nevertheless, secretory metabolites were the major contributing factor towards improved gut microvilli morphology, relieved stress status, and reduced intestinal inflammation of Nile tilapia fed diets supplemented with baker's yeast.
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