ArticleClinical oral investigations2016
Prevalence of Candida albicans and Candida dubliniensis in caries-free and caries-active children in relation to the oral microbiota-a clinical study.
Article in Clinical oral investigations, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Oral Candida-biome and Early Childhood Caries: A Systematic Review and Meta-Analysis.International dental journal · 2025Pooled it
- Influence of Filler Content and Polishing onThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025Article
- Antibiofilm potential of plant extracts: inhibiting oral microorganisms andFrontiers in dental medicine · 2025Article
- Interactions between non-Journal of oral microbiology · 2025Article
- Adaptation to Sodium Hypochlorite and Potassium Permanganate May Lead to Their Ineffectiveness AgainstPharmaceuticals (Basel, Switzerland) · 2024Article
- The Associations between Snack Intake and Cariogenic Oral Microorganism Colonization in Young Children of a Low Socioeconomic Status.Nutrients · 2024Article
- The Evolving Microbiome of Dental Caries.Microorganisms · 2024Review
- Evaluation of Changes in Oral Microflora in Children with Early Childhood Caries after Full Mouth Rehabilitation.International journal of clinical pediatric dentistry · 2024Article
- Effects of Nystatin oral rinse on oral Candida species and Streptococcus mutans among healthy adults.Clinical oral investigations · 2023Article
- Article
- Critically Appraising the Significance of the Oral Mycobiome.Journal of dental research · 2021Review
- Oral Mycobiome Differences in Various Spatial Niches With and Without Severe Early Childhood Caries.Frontiers in pediatrics · 2021Article
- Characterization of Supragingival Plaque and Oral Swab Microbiomes in Children With Severe Early Childhood Caries.Frontiers in microbiology · 2021Article
- Oral microbiome in down syndrome and its implications on oral health.Journal of oral microbiology · 2020Article
- Spatial Design of Polymicrobial Oral Biofilm in Its Native Disease State.Journal of dental research · 2020Article
- Site-Specific Profiling of the Dental Mycobiome Reveals Strong Taxonomic Shifts during Progression of Early-Childhood Caries.Applied and environmental microbiology · 2020Article
- Oral health and Candida carriage in socioeconomically disadvantaged US pregnant women.BMC pregnancy and childbirth · 2019Article
- Combined Candida dubliniensis and Candida albicans Keratitis following a Chemical Injury.Case reports in ophthalmological medicine · 2019Article
- Phenotypic and genotypic detection of Candida albicans and Candida dubliniensis strains isolated from oral mucosa of AIDS pediatric patients.Revista do Instituto de Medicina Tropical de Sao Paulo · 2017Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe correlation between caries and the oral prevalence of Candida spp. in children is contradictory in literature. Thereby, authors focused on Candida albicans as the most isolated Candida species from the oral cavity. Therefore, the aim of the present study was to compare caries-free and caries-bearing children regarding their oral carriage of Candida spp. MATERIAL AND
methodsTwenty-six caries-free (CF group) and 26 caries-active children (CA group) were included into this study. Three different types of specimens were assessed, saliva and plaque, and in the case of caries, infected dentine samples were microbiologically analyzed for aerobic and anaerobic microorganisms and their counts. Special attention was given to the differentiation between C. albicans and Candida dubliniensis. Additionally, different biochemical tests, VITEK 2 (VITEK®2, bioMérieux, Marcy-l'Etoile, France) and 16S and 18S ribosomal DNA (rDNA) sequencing, were applied for identification.
resultsThe detection of C. albicans did not differ between the CF and CA groups. C. dubliniensis was never detected in any specimen of the CF group, but occurred in one quarter of the CA group (27 % in plaque, 23 % in saliva), thus leading to a statistically significant difference between the two groups (p < 0.05). In six of these cases, C. dubliniensis was detected concomitantly in saliva and plaque and once only in plaque. CA group harbored statistically more Streptococcus mutans than the control group revealing a correlation between S. mutans and C. dubliniensis regarding the caries group.
conclusionsThis is the first study reporting a frequent detection of C. dubliniensis in caries-active children, which could have been underestimated so far due to difficulties in differentiation between this yeast species and C. albicans. CLINICAL RELEVANCE: Microbiological diagnostic-especially of oral Candida species-is an important determinant for identifying etiological factors of dental caries in children.
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