ArticleRespiratory research2015
Prenatal tobacco smoke exposure increases hospitalizations for bronchiolitis in infants.
Article in Respiratory research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 40 citations in OpenAlex.
- Parental Smoking and Risk of Allergic Conjunctivitis in Chinese Pediatric Population: A Cross-Sectional Study.Journal of asthma and allergy · 2025Article
- Health effects associated with exposure to secondhand smoke: a Burden of Proof study.Nature medicine · 2024Article
- Gut, oral, and nasopharyngeal microbiota dynamics in the clinical course of hospitalized infants with respiratory syncytial virus bronchiolitis.Frontiers in cellular and infection microbiology · 2023Article
- National, longitudinal NASCITA birth cohort study to investigate the health of Italian children and potential influencing factors.BMJ open · 2022Observational
- Time-Specific Factors Influencing the Development of Asthma in Children.Biomedicines · 2022Review
- The First 1000 Days: Impact of Prenatal Tobacco Smoke Exposure on Hospitalization Due to Preschool Wheezing.Healthcare (Basel, Switzerland) · 2021Article
- Severity of bronchiolitis in infants is associated with their parents' tobacco habit.European journal of pediatrics · 2021Observational
- Prenatal and Perinatal Environmental Influences Shaping the Neonatal Immune System: A Focus on Asthma and Allergy Origins.International journal of environmental research and public health · 2021Review
- Informatics Methodology Used in the Web-Based Portal of the NASCITA Cohort Study: Development and Implementation Study.Journal of medical Internet research · 2021Article
- Particulate Matter Exposure During Oocyte Maturation: Cell Cycle Arrest, ROS Generation, and Early Apoptosis in Mice.Frontiers in cell and developmental biology · 2020Article
- Associations of household environmental tobacco smoke exposure with respiratory symptoms and utilisation of medical services in healthy young children in Hong Kong.Tobacco induced diseases · 2020Article
- Prenatal and postnatal tobacco smoke exposure and risk of severe bronchiolitis during infancy.Respiratory medicine · 2018Article
- Tobacco Use and Smoke Exposure in Children: New Trends, Harm, and Strategies to Improve Health Outcomes.Current allergy and asthma reports · 2017Review
- The association between environmental tobacco smoke exposure and childhood respiratory disease: a review.Expert review of respiratory medicine · 2017Review
- Exposure to fine particulate matter in the air alters placental structure and the renin-angiotensin system.PloS one · 2017Article
- Negative Temperature Differential in Preterm Infants Less Than 29 Weeks Gestational Age: Associations With Infection and Maternal Smoking.Nursing researchArticle
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTobacco smoke exposure (TSE) is a worldwide health problem and it is considered a risk factor for pregnant women's and children's health, particularly for respiratory morbidity during the first year of life. Few significant birth cohort studies on the effect of prenatal TSE via passive and active maternal smoking on the development of severe bronchiolitis in early childhood have been carried out worldwide.
methodsFrom November 2009 to December 2012, newborns born at ≥ 33 weeks of gestational age (wGA) were recruited in a longitudinal multi-center cohort study in Italy to investigate the effects of prenatal and postnatal TSE, among other risk factors, on bronchiolitis hospitalization and/or death during the first year of life.
resultsTwo thousand two hundred ten newborns enrolled at birth were followed-up during their first year of life. Of these, 120 (5.4%) were hospitalized for bronchiolitis. No enrolled infants died during the study period. Prenatal passive TSE and maternal active smoking of more than 15 cigarettes/daily are associated to a significant increase of the risk of offspring children hospitalization for bronchiolitis, with an adjHR of 3.5 (CI 1.5-8.1) and of 1.7 (CI 1.1-2.6) respectively.
conclusionsThese results confirm the detrimental effects of passive TSE and active heavy smoke during pregnancy for infants' respiratory health, since the exposure significantly increases the risk of hospitalization for bronchiolitis in the first year of life.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.