ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2016
Postural blood pressure electrocardiographic changes are associated with falls in older people.
Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Cardiovascular Disorders and Falls Among Older Adults: A Systematic Review and Meta-Analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Pooled it
- Prevalence of initial orthostatic hypotension in older adults: a systematic review and meta-analysis.Age and ageing · 2021Pooled it
- Central command suppresses pressor-evoked bradycardia at the onset of voluntary standing up in conscious cats.Experimental physiology · 2023Article
- Feasibility of Diagnosing Initial Orthostatic Hypotension Using a Continuous Blood Pressure Device in Geriatric Rehabilitation Inpatients: RESORT.Gerontology · 2022Article
- Initial orthostatic hypotension and orthostatic intolerance symptom prevalence in older adults: A systematic review.International Journal of Cardiology. Hypertension · 2021Review
- Blood Pressure Drop Rate After Standing Up Is Associated With Frailty and Number of Falls in Geriatric Outpatients.Journal of the American Heart Association · 2020Article
- Orthostatic blood pressure changes and physical, functional and cognitive performance: the MELoR study.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2020Observational
- Multimodal Monitoring of Cardiovascular Responses to Postural Changes.Frontiers in physiology · 2020Article
- Rapid Systolic Blood Pressure Changes After Standing Up Associate With Impaired Physical Performance in Geriatric Outpatients.Journal of the American Heart Association · 2018Article
- Stroke and Falls-Clash of the Two Titans in Geriatrics.Geriatrics (Basel, Switzerland) · 2016Review
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine the magnitude of postural blood pressure change, differences in ECG between fallers and non-fallers were measured. Postural blood pressure change is associated with symptoms of dizziness, presyncope, and syncope.
methodsIn this cross-sectional study were included participants from The Malaysian Falls Assessment and Intervention Trial: fallers, aged 65 years or older with two or more falls or one injurious fall in 12 months, from a teaching hospital; and non-fallers, aged 65 years and older found through word-of-mouth and advertising. Noninvasive beat-to-beat blood pressure was measured at 10 min supine rest and 3 min standing. The maximal drop in systolic and diastolic pressure was calculated from a 12-lead ECG interpreted by a cardiologist. Basic demographics, medical history, and symptoms of dizziness, presyncope, and syncope were recorded for all patients.
resultsWe recruited 155 fallers and 112 non-fallers. Fallers had a significantly longer PR interval (179 ± 32 vs. 168 ± 27 ms, p = 0.013) and a longer corrected QT interval (449 ± 41 vs. 443 ± 39 msec, p = 0.008), and larger change in SBP (28 ± 14 vs. 19 ± 9 mmHg, p < 0.001) with posture change. SBP drop of ≥30mmHg associated with recurrent and injurious falls [odds ratio [95 % confidence interval] = 7.61 (3.18-18.21)]. The changes remained significant after adjustment for symptoms of dizziness, presyncope and syncope.
interpretationOlder individuals with recurrent and injurious falls have significantly longer PR and QT intervals and larger SBP reduction with posture change as compared to non-fallers, and these are not explained by the presence of dizziness, presyncope, or syncope. SBP cut-off of ≥30mmHg considered for postural measurements using continuous BP monitors, the significance of this value needs to be evaluated.
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