Evidence map›Paper›PMID 26695400›Full record

ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2016

Sleep disorders in patients with postural tachycardia syndrome.

Mitchell G Miglis, Srikanth Muppidi, Cynthia Feakins, Lori Fong, Thomas Prieto, Safwan Jaradeh

Abstract read
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In one paragraph

Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Faintly tired: a systematic review of fatigue in patients with orthostatic syncope.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Autonomic dysfunction in sleep disorders: introduction to the series.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2018
    Article
  6. Cognitive and psychological issues in postural tachycardia syndrome.Autonomic neuroscience : basic & clinical · 2018
    Review
  7. Review
  8. Health-related quality of life and suicide risk in postural tachycardia syndrome.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2017
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mitchell G MiglisDivision of Autonomic Neurology, Stanford University Medical Center, 211 Quarry Rd, 2nd Fl, MC 5992, Stanford, CA, 94305, USA. mmiglis@stanford.edu.
Srikanth MuppidiDivision of Autonomic Neurology, Stanford University Medical Center, 211 Quarry Rd, 2nd Fl, MC 5992, Stanford, CA, 94305, USA.
Cynthia FeakinsDivision of Autonomic Neurology, Stanford University Medical Center, 211 Quarry Rd, 2nd Fl, MC 5992, Stanford, CA, 94305, USA.
Lori FongDivision of Autonomic Neurology, Stanford University Medical Center, 211 Quarry Rd, 2nd Fl, MC 5992, Stanford, CA, 94305, USA.
Thomas PrietoDivision of Autonomic Neurology, Stanford University Medical Center, 211 Quarry Rd, 2nd Fl, MC 5992, Stanford, CA, 94305, USA.
Safwan JaradehDivision of Autonomic Neurology, Stanford University Medical Center, 211 Quarry Rd, 2nd Fl, MC 5992, Stanford, CA, 94305, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePatients with postural tachycardia syndrome (POTS) often describe symptoms of fatigue, sleepiness, and lack of refreshing sleep. We aimed to provide further objective measures of sleep in patients with POTS.

methodsPOTS patients (n = 18) were selected based on autonomic testing and evaluation at our center. Controls (n = 16) of similar age, gender, and BMI were selected from new patients referred to the Stanford Sleep Disorders Clinic for any sleep-related complaint. All patients underwent polysomnography and completed several sleep questionnaires and a 2-week sleep diary.

resultsPOTS patients and control subjects were of similar age (27 ± 10.2 vs. 29 ± 5.4 years, p = 0.92) and Body Mass Index (21 ± 3.8 vs. 24 ± 4.1, p = 0.14). The majority of subjects in both groups were females (72 % POTS vs. 81 % controls). POTS patients scored higher on subjective fatigue scales but not sleepiness scales. POTS patients scored in the normal range on the BDI and the "evening" category on the MEQ. Their sleep diaries were not different from controls. With the exception of mild OSA, slightly reduced %REM and prolonged REM latency, their PSG data were normal and no different from controls.

conclusionsIt is unlikely that the sleep-related complaints of POTS patients are the result of a primary sleep disorder unique to POTS. We propose that a combination of factors such as body fatigue, chronic pain, and other somatic symptoms common in POTS patients might be the underlying reason for sleep-related symptoms in POTS.

Indexed as

AdultFatigueFemaleHumansMaleMedical RecordsPolysomnographyPostural Orthostatic Tachycardia SyndromeSleep Wake DisordersSurveys and QuestionnairesFatigueOrthostaticPostural tachycardia syndromeSleepSleepiness

Identifiers

PMID26695400

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.