Evidence map›Paper›PMID 26695093›Full record

ArticleFly2015

Don't pull the plug! the Drosophila mating plug preserves fertility.

Frank W Avila, Alex Wong, Jessica L Sitnik, Mariana F Wolfner

Abstract read
In one paragraph

Article in Fly, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. A Male Expressed Copulatory Plug Increases Female Fertility inbioRxiv : the preprint server for biology · 2026
    Article
  2. Female genetic variation controlling timing of mating plug ejection inbioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Finishing the egg.Genetics · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Frank W Avilaa Department of Molecular Biology and Genetics ; Cornell University ; Ithaca , NY , USA.
Alex Wongb Department of Biology ; Carleton University ; Ottawa , Ontario , Canada.
Jessica L Sitnika Department of Molecular Biology and Genetics ; Cornell University ; Ithaca , NY , USA.
Mariana F Wolfnera Department of Molecular Biology and Genetics ; Cornell University ; Ithaca , NY , USA.

Funding

ACTIONS OF SEMINAL PROTEINS IN MATED DROSOPHILA FEMALESR01HD038921 · NICHD · CORNELL UNIVERSITY ITHACA · PI WOLFNER, MARIANA FEDERICA · 2000 to 2019
$5.6M
Reproductive Sciences and Genomics Training ProgramT32HD052471 · NICHD · CORNELL UNIVERSITY · PI ROBERSON, MARK S · 2007 to 2016
$2.0M
NICHD NIH HHS R01 HD038921NICHD NIH HHS R01-HD038921NICHD NIH HHS T32 HD052471
6 · The paper itself

Abstract

Mating plugs are hardened structures--typically a coagulation of seminal fluid components--that are transferred to, or formed within, the female reproductive tract of numerous animal species (both mammals and insects). Analysis of the role(s) of the mating plug in reproduction has been conducted in a wide array of diverse species. These structures have been proposed to have a multitude of functions, which include altering female re-mating rate, acting as a barrier to re-mating and being required for sperm storage or sperm movement to occur in mated females. A recent analysis of the Drosophila melanogaster mating plug has shown that proper formation of the structure is required for optimal fertility in flies: the Drosophila mating plug is required to retain the ejaculate within the female reproductive tract once mating has terminated. Here, we discuss the possible implications of the Drosophila mating plug in the fertility of this species in light of these new results.

Indexed as

AnimalsDrosophila melanogasterEjaculationFemaleFertilityGenitalia, FemaleMaleSexual Behavior, AnimalSpermatozoaDrosophila reproductionmating plugPEBmesperm storage

Identifiers

PMID26695093
PMCPMC4826122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.