Evidence map›Paper›PMID 26694063›Full record

ReviewDysphagia2016

The Physiology of Eructation.

Ivan M Lang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Dysphagia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Demographic Factors in Pharyngoesophageal Segment Size: A Scoping Review.Laryngoscope investigative otolaryngology · 2026
    Review
  3. The pharyngeal phase of swallowing controls deglutitive inhibition.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  4. Effects of esophageal acidification on esophageal reflexes controlling the upper esophageal sphincter.American journal of physiology. Gastrointestinal and liver physiology · 2019
    Article
  5. Characterization and mechanisms of the supragastric belch in the cat.American journal of physiology. Gastrointestinal and liver physiology · 2017
    Article
  6. Review
  7. Characterization and mechanisms of the pharyngeal swallow activated by stimulation of the esophagus.American journal of physiology. Gastrointestinal and liver physiology · 2016
    Article
  8. Article
  9. Supragastric belching: Pathogenesis, diagnostic issues and treatment.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ivan M LangDivision of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, 53226, USA. imlang@mcw.edu.
Medical College of Wisconsin · US

Funding

The Physiology of the Pharyngo-Esophageal JunctionP01DK068051 · NIDDK · MEDICAL COLLEGE OF WISCONSIN · PI SHAKER, REZA NONE · 2007 to 2018
$11.6M
NIDDK NIH HHS P01DK068051
6 · The paper itself

Abstract

Eructation is composed of three independent phases: gas escape, upper barrier elimination, and gas transport phases. The gas escape phase is the gastro-LES inhibitory reflex that causes transient relaxation of the lower esophageal sphincter, which is activated by distension of stretch receptors of the proximal stomach. The upper barrier elimination phase is the transient relaxation of the upper esophageal sphincter along with airway protection. This phase is activated by stimulation of rapidly adapting mechanoreceptors of the esophageal mucosa. The gas transport phase is esophageal reverse peristalsis mediated by elementary reflexes, and it is theorized that this phase is activated by serosal rapidly adapting tension receptors. Alteration of the receptors which activate the upper barrier elimination phase of eructation by gastro-esophageal reflux of acid may in part contribute to the development of supra-esophageal reflux disease.

Indexed as

EructationEsophageal MucosaEsophageal Sphincter, LowerEsophageal Sphincter, UpperGasesGastroesophageal RefluxHumansMechanoreceptorsPeristalsisStomachGasesBelchingEructationEsophageal reverse peristalsisEsophago-pharyngeal reflux (EPR)Supra-esophageal reflux disease (SERD)Transient relaxation of the lower esophageal sphincter (TLESR)Transient relaxation of the upper esophageal sphincter (TUESR)

Identifiers

PMID26694063
OpenAlexW2213347019

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.