Evidence map›Paper›PMID 26694034›Full record

ReviewMolecules and cells2015

The ETS Factor, ETV2: a Master Regulator for Vascular Endothelial Cell Development.

Se-Yeong Oh, Ju Young Kim, Changwon Park

Open access · diamondAbstract readReview
In one paragraph

Review in Molecules and cells, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 62 citations in OpenAlex.

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  8. Endothelial to mesenchymal transition: a central mechanism in diabetes-induced vascular pathology.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Se-Yeong OhDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
Ju Young KimDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
Changwon ParkDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
Emory University · US

Funding

Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Mechanisms of ER71/ETV2-regulated VascularizationR01HL119291 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PARK, CHANGWON · 2013 to 2022
$3.2M
NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1TR000454NHLBI NIH HHS R01 HL119291
6 · The paper itself

Abstract

Appropriate vessel development and its coordinated function is essential for proper embryogenesis and homeostasis in the adult. Defects in vessels cause birth defects and are an important etiology of diseases such as cardiovascular disease, tumor and diabetes retinopathy. The accumulative data indicate that ETV2, an ETS transcription factor, performs a potent and indispensable function in mediating vessel development. This review discusses the recent progress of the study of ETV2 with special focus on its regulatory mechanisms and cell fate determining role in developing mouse embryos as well as somatic cells.

Indexed as

Embryonic DevelopmentNeovascularization, PhysiologicAnimalsCell DifferentiationCellular ReprogrammingEndothelial CellsGene Expression Regulation, DevelopmentalHumansMiceTranscription FactorsER71 protein, mouseTranscription Factorscell reprogrammingendothelial cellsETV2transcription factors

Identifiers

PMID26694034
PMCPMC4696993
OpenAlexW2380741403

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.