Evidence map›Paper›PMID 26693920›Full record

ReviewMalaria journal2015

Ethical aspects of malaria control and research.

Euzebiusz Jamrozik, Vânia de la Fuente-Núñez, Andreas Reis, Pascal Ringwald, Michael J Selgelid

Open access · goldAbstract readReview
In one paragraph

Review in Malaria journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Exploring the relationship betweenThe Pan African medical journal · 2024
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Genetic Variation ofFrontiers in pharmacology · 2021
    Article
  12. Review
  13. A Multi-StageFrontiers in cellular and infection microbiology · 2019
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Euzebiusz JamrozikCentre for Human Bioethics, Monash University, Clayton, VIC, Australia. zeb.jamrozik@gmail.com.
Vânia de la Fuente-NúñezDepartment of Knowledge, Ethics and Research, World Health Organization, Geneva, Switzerland. delafuentenunez@who.int.
Andreas ReisDepartment of Knowledge, Ethics and Research, World Health Organization, Geneva, Switzerland. reisa@who.int.
Pascal RingwaldGlobal Malaria Programme, World Health Organization, Geneva, Switzerland. ringwaldp@who.int.
Michael J SelgelidCentre for Human Bioethics, Monash University, Clayton, VIC, Australia. michael.selgelid@monash.edu.
World Health Organization · CHMonash University · AU

Funding

World Health Organization 001
6 · The paper itself

Abstract

Malaria currently causes more harm to human beings than any other parasitic disease, and disproportionally affects low-income populations. The ethical issues raised by efforts to control or eliminate malaria have received little explicit analysis, in comparison with other major diseases of poverty. While some ethical issues associated with malaria are similar to those that have been the subject of debate in the context of other infectious diseases, malaria also raises distinct ethical issues in virtue of its unique history, epidemiology, and biology. This paper provides preliminary ethical analyses of the especially salient issues of: (i) global health justice, (ii) universal access to malaria control initiatives, (iii) multidrug resistance, including artemisinin-based combination therapy (ACT) resistance, (iv) mandatory screening, (v) mass drug administration, (vi) benefits and risks of primaquine, and (vii) malaria in the context of blood donation and transfusion. Several ethical issues are also raised by past, present and future malaria research initiatives, in particular: (i) controlled infection studies, (ii) human landing catches, (iii) transmission-blocking vaccines, and (iv) genetically-modified mosquitoes. This article maps the terrain of these major ethical issues surrounding malaria control and elimination. Its objective is to motivate further research and discussion of ethical issues associated with malaria--and to assist health workers, researchers, and policy makers in pursuit of ethically sound malaria control practice and policy.

Indexed as

AntimalarialsBiomedical ResearchCommunicable Disease ControlGlobal HealthHealth Services AccessibilityHumansMalariaAntimalarials

Identifiers

PMID26693920
PMCPMC4688922
OpenAlexW2202717106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.