Supporting data for the characterization of PNA-DNA four-way junctions.

Douglas Iverson, Crystal Serrano, Ann Marie Brahan, Arik Shams, Filbert Totsingan, Anthony J Bell

Abstract read

In one paragraph

Article in Data in brief, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Nucleic acid nanostructures forApplied physics reviews · 2023
Review
Conformation and protein interactions of intramolecular DNA and phosphorothioate four-way junctions.Experimental biology and medicine (Maywood, N.J.) · 2021
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Douglas IversonDepartment of Chemistry and Biochemistry, The University of Southern Mississippi, Hattiesburg, MS, USA.

Crystal SerranoDepartment of Chemistry and Biochemistry, The University of Southern Mississippi, Hattiesburg, MS, USA.

Ann Marie BrahanDepartment of Chemistry and Biochemistry, The University of Southern Mississippi, Hattiesburg, MS, USA.

Arik ShamsDepartment of Chemistry and Biochemistry, The University of Southern Mississippi, Hattiesburg, MS, USA.

Filbert TotsinganDepartment of Chemistry, New York University, New York, NY, USA.

Anthony J BellDepartment of Chemistry and Biochemistry, The University of Southern Mississippi, Hattiesburg, MS, USA.

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MICHAEL R GARRETT · 2012 to 2026

$60.2M

NIGMS NIH HHS P20 GM103476

6 · The paper itself

Abstract

Holliday or DNA four-way junctions (4WJs) are cruciform/bent structures composed of four DNA duplexes. 4WJs are key intermediates in homologous genetic recombination and double-strand break repair. To investigate 4WJs in vitro, junctions are assembled using four asymmetric DNA strands. The presence of four asymmetric strands about the junction branch point eliminates branch migration, and effectively immobilizes the resulting 4WJ. The purpose of these experiments is to show that immobile 4WJs composed of DNA and peptide nucleic acids (PNAs) can be distinguished from contaminating labile nucleic acid structures. These data compare the electrophoretic mobility of hybrid PNA-DNA junctions vs. i) a classic immobile DNA 4WJ, J1 and ii) contaminating nucleic acid structures.

Identifiers

PMID26693508

DOI10.1016/j.dib.2015.10.013

PMCPMC4659781

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.