ArticleIndian journal of endocrinology and metabolism
Aspergillus species: An emerging pathogen in onychomycosis among diabetics.
Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 27 citations in OpenAlex.
- Prevalence and Risk Factors Predicting Onychomycosis in Patients with and Without Diabetes Mellitus in Spain: A Cross-Sectional Study.Journal of fungi (Basel, Switzerland) · 2024Article
- Onychomycosis in Patients with Diabetes Mellitus in Africa: A Global Scoping Review, 2000-2021.Mycopathologia · 2023Article
- Gut mycobiome dysbiosis in rats showing retinal changes indicative of diabetic retinopathy.PloS one · 2022Article
- Review
- Comparative Study of Traditional Ablative COClinical drug investigation · 2020Article
- A 9-Year Experience ofInfection and drug resistance · 2020Article
- Zombie Cells, Composite Cells of Fungal-Human Keratinocytes of Plantar Hyperkeratosis-Like Lesions.Mycopathologia · 2019Article
- A Review of Onychomycosis Due to Aspergillus Species.Mycopathologia · 2018Review
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionApproximately, 33% patients with diabetes are afflicted with onychomycosis. In the past, nondermatophyte molds have been regarded as opportunistic pathogens; recently, Aspergillus species are considered as emerging pathogens of toenail infections. In Sri Lanka, the prevalence of Aspergillus species in onychomycosis among diabetics is not well documented.
objectiveTo determine the proportion of Aspergillus onychomycosis, risk factors and knowledge among diabetics. MATERIALS AND
methodsThis was descriptive cross-sectional study. Three hundred diabetic patients were included. Clinical examinations of patients' toenails were performed by a clinical microbiologist. Laboratory identification was done, and pathogens were identified to the species level by morpho-physiological methods. All inferential statistics were tested at P < 0.05.
resultsAmong clinically suspected patients, 85% (255/300) were mycologically confirmed to have onychomycosis. Aspergillus species were most commonly isolated n = 180 (71%) followed by dermatophytes, yeasts, and other molds n = 75 (29%). Of the patients having Aspergillus onychomycosis, 149 (83%) were in the > age group. In men, Aspergillus onycomycosis was seen in 82%. Among patients who had Aspergillus nail infection, 114 (63%) had diabetes for a period of > years. Among patients who were engaged in agricultural activities, 77% were confirmed to have infected nails due to Aspergillus species.
conclusionAspergillus niger was the most common pathogen isolated from toenail infection. Aspergillus species should be considered as an important pathogen in toenail onychomycosis in diabetic patients. Risk factors associated with Aspergillus onychomycosis were age, gender, duration of diabetes, length of exposure to fungi, and occupation.
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