ArticleIndian journal of endocrinology and metabolism
To assess vascular calcification in the patients of hypoparathyroidism using multidetector computed tomography scan.
Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Cardiovascular Morbidity and Mortality in Chronic Hypoparathyroidism: A Systematic Review and Meta-Analysis.Calcified tissue international · 2026Pooled it
- Arrhythmic burden of long-term postsurgical hypoparathyroidism assessed with 24-hour Holter ECG.Endocrine · 2025Article
- Increased arterial stiffness in normotensive individuals with hypoparathyroidism.Scientific reports · 2025Article
- Presentation of hypoparathyroidism in Italy: a nationwide register-based study.Journal of endocrinological investigation · 2024Article
- Coronary calcium score in patients with post-surgical hypoparathyroidism.Archives of endocrinology and metabolism · 2024Article
- Assessment of Calcium Score Cutoff Point for Clinically Significant Aortic Stenosis on Lung Cancer Screening Program Low-Dose Computed Tomography-A Cross-Sectional Analysis.Diagnostics (Basel, Switzerland) · 2023Article
- Hyperphosphatemia is associated with cardiac valve calcification in chronic hypoparathyroidism.Journal of endocrinological investigation · 2022Article
- Coronary artery calcification progression and long-term cardiovascular outcomes in renal transplant recipients: an analysis by the joint model.Clinical kidney journal · 2022Article
- Lower Leg Arterial Calcifications Assessed by High-Resolution Peripheral Quantitative Computed Tomography in Hypoparathyroid and Pseudohypoparathyroid Patients.Calcified tissue international · 2021Article
- Bone marrow mesenchymal stem cell exosomes suppress phosphate-induced aortic calcification via SIRT6-HMGB1 deacetylation.Stem cell research & therapy · 2021Article
- A Case of Critical Lower-Limb Ischemia in a 29-Year-Old Man with Autoimmune Polyglandular Syndrome Type 1 (APS-1).The American journal of case reports · 2020Article
- Prevalence of basal ganglia and carotid artery calcifications in patients with permanent hypoparathyroidism after total thyroidectomy.Endocrine connections · 2020Article
- Central and peripheral blood pressures and arterial stiffness increase in hypoparathyroidism.Archives of endocrinology and metabolism · 2020Article
- Postoperative Hypoparathyroidism: Prognosis, Prevention, and Treatment (Review).Sovremennye tekhnologii v meditsine · 2020Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur pilot data showed an increased intima media thickness in the patients with sporadic idiopathic hypoparathyroidism (SIH). Alteration in homeostasis of calcium, phosphate, and parathyroid hormone (PTH) may predispose to increase the risk of cardiovascular morbidity and mortality. The data on objective assessment of this increased risk is however lacking.
objectiveTo assess the effect of altered calcium, phosphate, and PTH homeostasis in the patients with SIH on coronary calcium score (a marker of increase vascular risk) by multidetector computed tomography scan (MDCT).
methodsIn this case-control study, we measured coronary CT calcium score in 30 patients of SIH and compared with 40 age and sex matched healthy subjects. Correlation of coronary calcium score with biochemical parameters was evaluated.
resultsThree of the 30 cases (10%) with SIH were found to have coronary artery calcification (CAC) of varying degree, whereas none of the control showed CAC (P = 0.07). The patients with CAC had significantly lower serum calcium levels (albumin corrected), as compared to the patients without CAC. Inverse correlation of CAC was found with serum calcium levels. No correlation was found with other biochemical parameters.
conclusionThe vascular risk is increased in the patients with SIH as assessed by coronary calcium score measured by MDCT. Low serum calcium levels might be a predisposing factor for this increased risk.
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