Trial reportBMJ open2015
Relationship of anthropometric measurements to thyroid nodules in a Chinese population.
Trial report in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01838629 (the Effect of Universal Salt Iodization on Thyroid Diseases), which is not on this map. Cited by 38 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
the Effect of Universal Salt Iodization on Thyroid Diseases
Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Mapping global epidemiology of thyroid nodules among general population: A systematic review and meta-analysis.Frontiers in oncology · 2022Pooled it
- The Relationship and Gender Disparity Between Thyroid Nodules and Metabolic Syndrome Components Based on a Recent Nationwide Cross-Sectional Study and Meta-Analysis.Frontiers in endocrinology · 2021Pooled it
- 2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS.Endocrine · 2020Guideline
- Article
- Adiposity Is Associated with a Higher Risk of Thyroid Malignancy in Patients with Hashimoto's Thyroiditis.Diagnostics (Basel, Switzerland) · 2025Article
- Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomes.European thyroid journal · 2025Article
- Effects of Overweight on Risk of Thyroid Nodules in Children and Adolescents: The Fukushima Health Management Survey.The Journal of clinical endocrinology and metabolism · 2025Article
- Association of Body Mass Index trajectory with thyroid nodules during young adulthood in China.Scientific reports · 2025Article
- Association of gender and metabolic factors with thyroid nodules in T2DM: a retrospective study.PeerJ · 2025Article
- Article
- Establishment and validation of a multivariate logistic model for risk factors of thyroid nodules using lasso regression screening.Frontiers in endocrinology · 2024Article
- Risk factors associated with the prevalence of thyroid nodules in adults in Northeast China: a cross-sectional population-based study.BMJ open · 2023Article
- Clinical value of grayscale ultrasound combined with real-time shear wave elastography nomogram in risk prediction of thyroid cancer.BMC medical imaging · 2023Article
- Thyroid Nodules and Obesity.Life (Basel, Switzerland) · 2023Review
- Comparison of diagnostic performance and FNA management of the ACR-TIRADS and Chinese-TIRADS based on surgical histological evidence.Quantitative imaging in medicine and surgery · 2023Article
- Detection of Thyroid Nodule Prevalence and Associated Risk Factors in Southwest China: A Study of 45,023 Individuals Undergoing Physical Examinations.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- OPG is associated with thyroid nodule development in type 2 diabetes.Journal of clinical laboratory analysis · 2022Article
- Prevalence and associated metabolic factors for thyroid nodules: a cross-sectional study in Southwest of China with more than 120 thousand populations.BMC endocrine disorders · 2021Article
- Thyroid imaging reporting and data system (TIRADS) for ultrasound features of nodules: multicentric retrospective study in China.Endocrine · 2021Article
- Cost-Effectiveness Analysis of Ultrasound Screening for Thyroid Cancer in Asymptomatic Adults.Frontiers in public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePrevious studies have found that overweight and obesity are related to numerous diseases, including thyroid cancer and thyroid volume. This study evaluates the relationship between body size and the presence of thyroid nodules in a Chinese population.
methodsA total of 6793 adults and 2410 children who underwent thyroid ultrasonography were recruited in this cross-sectional study in Hangzhou, Zhejiang Province, China, from March to October, 2010. Sociodemographic characteristics and potential risk factors of thyroid nodules were collected by questionnaire. Height and weight were measured using standard protocols. Associations of height, weight, body mass index (BMI) and body surface area (BSA) with the presence of thyroid nodules were evaluated using multiple logistic regression models.
resultsAfter adjustment for potential risk factors, an increased risk of thyroid nodule incidence was associated with height (OR 1.15, 95% CI 1.02 to 1.30), weight (OR 1.40, 95% CI 1.24 to 1.58), BMI (OR 1.26, 95% CI 1.11 to 1.42) and BSA (OR 1.43, 95% CI 1.27 to 1.62) in all adults, but most obviously in women. In children, similar associations were observed between risk of thyroid nodule incidence and weight, BMI and BSA, but not height. BSA was the measurement most significantly associated with thyroid nodules in both adults and children.
conclusionsThis study identified that the presence of thyroid nodules was positively associated with weight, height, BMI and BSA in both women and girls. It suggests that tall, obese individuals have increased susceptibility to thyroid nodules. TRIAL REGISTRATION NUMBER: NCT01838629.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.