ArticleGenetics and molecular biology2015
NCAPG is differentially expressed during longissimus muscle development and is associated with growth traits in Chinese Qinchuan beef cattle.
Article in Genetics and molecular biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
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- LCORL and STC2 Variants Increase Body Size and Growth Rate in Cattle and Other Animals.Genomics, proteomics & bioinformatics · 2025Article
- Transcriptional Signatures of Domestication Revealed through Meta-Analysis of Pig, Chicken, Wild Boar, and Red Junglefowl Gene Expression Data.Animals : an open access journal from MDPI · 2024Article
- Unlocking the Transcriptional Control ofInternational journal of molecular sciences · 2024Article
- Genomic Selection for Live Weight in the 14th Month in Alpine Merino Sheep Combining GWAS Information.Animals : an open access journal from MDPI · 2023Article
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- Genome-wide association and genotype by environment interactions for growth traits in U.S. Red Angus cattle.BMC genomics · 2022Article
- NCAPG Promotes the Proliferation of Renal Clear Cell Carcinoma via Mediating with CDK1.Disease markers · 2022Article
- Genome-wide association analyses of carcass traits using copy number variants and raw intensity values of single nucleotide polymorphisms in cattle.BMC genomics · 2021Article
- Key Genes Regulating Skeletal Muscle Development and Growth in Farm Animals.Animals : an open access journal from MDPI · 2021Review
- Genetic diversity and population structure in divergent German cattle selection lines on the basis of milk protein polymorphisms.Archives animal breeding · 2021Article
- Associations between maternal milk protein genotypes with preweaning calf growth traits in beef cattle.Journal of animal science · 2020Article
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- Genome-wide association and genotype by environment interactions for growth traits in U.S. Gelbvieh cattle.BMC genomics · 2019Article
- Genetic Characterization of Indubrasil Cattle Breed Population.Veterinary sciences · 2018Article
- Scans for signatures of selection in Russian cattle breed genomes reveal new candidate genes for environmental adaptation and acclimation.Scientific reports · 2018Article
- High-resolution analysis of selection sweeps identified between fine-wool Merino and coarse-wool Churra sheep breeds.Genetics, selection, evolution : GSE · 2017Article
- Searching for new loci and candidate genes for economically important traits through gene-based association analysis of Simmental cattle.Scientific reports · 2017Article
- Multi-strategy genome-wide association studies identify the DCAF16-NCAPG region as a susceptibility locus for average daily gain in cattle.Scientific reports · 2016Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Based on RNA-seq analysis, we recently found that the bovine NCAPG (non-SMC condensin I complex, subunit G) gene is differentially expressed during development of the longissimus muscle. In the present study, we validated this result and, using quantitative real-time PCR analysis, identified two adjacent genes, LCORL and DCAF16, that are more abundant in fetal muscle tissue; further analysis of tissue-specific expression patterns indicated high abundance of NCAPG in muscle. Since no polymorphisms were detected in a previous study of Qinchuan cattle, we extended our investigation to examine the occurrence of single-nucleotide polymorphisms (SNPs) in the NCAPG gene. Three SNPs, i.e., one located in the intron region (g47747: T > G), a synonymous mutation (g52535: A > G) and a missense mutation (g53208: T > G) that leads to a change in the amino acid of interest (pIle442Met), were detected in a population of Qinchuan beef cattle (n = 300). Association analysis showed that these SNPs were significantly associated with the growth traits of Qinchuan beef cattle. Our results indicate that the bovine NCAPG gene may be involved in the development of the longissimus muscle. These polymorphisms in the NCAPG gene may be useful for marker-assisted selection of optimal body size in Qinchuan beef cattle.
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Registered trials
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