ArticleExperimental and clinical psychopharmacology2016
Impulsivity and polysubstance use: A systematic comparison of delay discounting in mono-, dual-, and trisubstance use.
Article in Experimental and clinical psychopharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- A systematic review and meta-analysis of delay discounting and cannabis use.Experimental and clinical psychopharmacology · 2021Pooled it
- Steep delay discounting and addictive behavior: a meta-analysis of continuous associations.Addiction (Abingdon, England) · 2017Pooled it
- Increases in striatal response to reward anticipation relate to reductions in impulsivity in women with substance use disorders.NeuroImage. Clinical · 2026Article
- Measurement of Impulsivity and Its Role in Drug Use Behaviours and Related Health, Harm and Treatment Outcomes Among People Who Use Illicit Drugs-A Scoping Review.International journal of mental health and addiction · 2026Article
- Daily patterns of single and poly-substance use among adolescent and young adult females: A day-level latent class analysis.Addictive behaviors · 2025Article
- Perceived reward certainty in the assessment of delay discounting.Journal of the experimental analysis of behavior · 2025Article
- Assessment of contextualized reinforcement pathology in a community sample of young adult substance users.Alcohol, clinical & experimental research · 2025Article
- Article
- Grade-Level Differences in the Profiles of Substance Use and Behavioral Health Problems: A Multi-Group Latent Class Analysis.International journal of environmental research and public health · 2024Article
- A comparative analysis of burden of care and coping styles between wives of monosubstance- and polysubstance-dependent men.Industrial psychiatry journal · 2024Article
- Delay discounting is associated with addiction and mental health measures while controlling for health behaviors and health barriers in a large US sample.Addictive behaviors reports · 2024Article
- Smoking Dependence, Time-Discounting, and Sustained Cessation Behavior: A Longitudinal Study of Predominantly Light Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Article
- The role of premeditation in suicide: Identifying factors associated with increased planning among suicide decedents.Journal of clinical psychology · 2023Article
- Patterns of polysubstance use and clinical comorbidity among persons seeking substance use treatment: An observational study.Journal of substance use and addiction treatment · 2023Observational
- Resilience profiles predict polysubstance use in adolescents with a history of childhood maltreatment.Addiction research & theory · 2023Article
- Investigating predictors of problematic alcohol, cannabis, and nicotine use among legal users of all three substances.Frontiers in psychiatry · 2023Article
- Delay discounting and neurocognitive performance in young adults with differential patterns of substance use: Findings from the Human Connectome Project.Experimental and clinical psychopharmacology · 2022Article
- Cognitions mediate the influence of personality on adolescent cannabis use initiation.Addictive behaviors reports · 2022Article
- Additive roles of tobacco and cannabis co-use in relation to delay discounting in a sample of heavy drinkers.Psychopharmacology · 2022Article
- Resting state functional connectivity in alcohol users and co-users of other substances.Psychiatry research. Neuroimaging · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Understanding the association between polysubstance use and impulsivity is pertinent to treatment planning and efficacy. Delay discounting, a measure of impulsivity, supplies the rate at which a reinforcer loses value as the temporal delay to its receipt increases. Excessive delay discounting has been widely observed among drug-using individuals, though the impact of using more than 1 substance has been only minimally studied. Here, after controlling for demographic variables, we systematically compared delay discounting in community controls, heavy smokers, and alcohol- and cocaine-dependent individuals to assess the impact of non-, mono-, dual-, and trisubstance use. All substance-using groups discounted significantly more than did community controls (p < .05). Additionally, groups that smoked cigarettes in addition to another substance dependency discounted significantly more than did the group that smoked cigarettes only (p < .05). Last, trisubstance users who were alcohol-dependent, cocaine-dependent, and heavy cigarette smokers discounted significantly more than did heavy smokers (p < .01). However, trisubstance users did not discount significantly more than did any dual-substance group. Trisubstance use was associated with greater impulsivity than was monosubstance smoking but exhibited no greater impulsivity than did dual-substance use, suggesting a ceiling effect on discounting when more than 2 substances are in use. The present study suggests that smokers who engage in additional substance use may experience worse treatment outcomes, given that excessive discounting is predictive of poor therapeutic outcomes in several studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.