Evidence map›Paper›PMID 26691697›Full record

ArticleJournal of the American Geriatrics Society2015

Association Between Objectively Measured Physical Activity and Cognitive Function in Older Adults-The Reasons for Geographic and Racial Differences in Stroke Study.

Wenfei Zhu, Virginia J Howard, Virginia G Wadley, Brent Hutto, Steven N Blair, John E Vena, Natalie Colabianchi, David Rhodes, Steven P Hooker

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

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  20. Weather Woes? Exploring Potential Links between Precipitation and Age-Related Cognitive Decline.International journal of environmental research and public health · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Wenfei ZhuInstitute of Sports Biology, Shaanxi Normal University, Shaanxi, China.
Virginia J HowardDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.
Virginia G WadleyDepartment of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Brent HuttoPrevention Research Center, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina.
Steven N BlairDepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina.
John E VenaDepartment of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Natalie ColabianchiInstitute for Social Research, University of Michigan, Ann Arbor, Michigan.
David RhodesDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.
Steven P HookerInstitute of Sports Biology, Shaanxi Normal University, Shaanxi, China.
University of Alabama at Birmingham · USUniversity of South Carolina · USArizona State University · USMedical University of South Carolina · USShaanxi Normal University · CNUniversity of Michigan–Ann Arbor · US

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
Impact of Physical Activity on Stroke and Cognitive Function in Older AdultsR01NS061846 · NINDS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI HOOKER, STEVEN PAUL · 2008 to 2012
$2.9M
NINDS NIH HHS R01 NS061846NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

objectivesTo examine the relationship between objectively measured physical activity (PA) and cognitive function in white and black older adults.

designCross-sectional.

settingREasons for Geographic and Racial Differences in Stroke (REGARDS) study.

participantsOlder adults who provided valid data from accelerometer and cognitive function tests (N = 7,098). MEASUREMENTS: Accelerometers provided estimates of PA variables for 4 to 7 consecutive days. PA cut-points of 50 counts per minute (cpm) and 1,065 cpm were applied to differentiate between being sedentary and light PA and between light and moderate to vigorous PA (MVPA), respectively. Prevalence of cognitive impairment was defined using the Six-Item Screener (<4/6). Letter fluency, animal fluency, word list learning, and Montreal Cognitive Assessment (orientation and recall) were used to assess memory and executive function.

resultsOf 7,098 participants (aged 70.1 ± 8.5, 54.2% female, 31.5% black), 359 (5.1%) had impaired cognition within ±12 months of PA measurement. The average proportion of time spent in MVPA (MVPA%) was 1.4 ± 1.9%. Participants in the highest quartile of MVPA% (~258.3 min/wk) were less likely to be cognitively impaired than those in the lowest quartile (odds ratio = 0.65, 95% confidence interval = 0.43-0.97). MVPA% was also significantly associated with executive function and memory z-scores (P < .001). Similar analyses of proportion of time spent in light PA (LPA%) and sedentary time (ST%) showed no significant associations with cognitive function.

conclusionHigher levels of objectively measured MVPA%, rather than LPA% or ST%, were associated with lower prevalence of cognitive impairment and better performance in memory and executive function in aging people. The amount of MVPA associated with lower prevalence of cognitive impairment is consistent with meeting PA guidelines.

Indexed as

accelerometryagingcognitive functionphysical activity

Identifiers

PMID26691697
PMCPMC4688903
OpenAlexW2200198500

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.