ArticleJournal of the American Geriatrics Society2015
Association Between Objectively Measured Physical Activity and Cognitive Function in Older Adults-The Reasons for Geographic and Racial Differences in Stroke Study.
Article in Journal of the American Geriatrics Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Total Sedentary Time and Cognitive Function in Middle-Aged and Older Adults: A Systematic Review and Meta-analysis.Sports medicine - open · 2022Pooled it
- Enhancing cognition in older adults with interactive wall exergames.Scientific reports · 2025Trial
- The Moderating Effect of Physical Activity on the Association Between Cognitive Function and Fear of Falling in Low-Income Community-Dwelling Older Adults.Research in gerontological nursing · 2026Article
- Associations of Accelerometer-Measured Physical Activity With Dementia, Anxiety, and Depression Among Older Adults.Journal of the American Geriatrics Society · 2025Article
- Circuit Training Improves the Levels of β-Amyloid and Brain-Derived Neurotrophic Factor Related to Cognitive Impairment Risk Factors in Obese Elderly Korean Women.Journal of clinical medicine · 2024Article
- Objectively measured levels of moderate to vigorous intensity physical activity are associated with cognitive impairment in diabetic hemodialysis patients: a cross-sectional study.Frontiers in medicine · 2024Article
- Ambient temperatures associated with reduced cognitive function in older adults in China.Scientific reports · 2023Article
- Move Your Body, Boost Your Brain: The Positive Impact of Physical Activity on Cognition across All Age Groups.Biomedicines · 2023Review
- The Associations of Loneliness and Social Support with Cognitive Impairment among Middle-Aged and Older Individuals with Diabetes.International journal of environmental research and public health · 2023Article
- A non-pharmacological multidomain intervention of dual-task exercise and social activity affects the cognitive function in community-dwelling older adults with mild to moderate cognitive decline: A randomized controlled trial.Frontiers in aging neuroscience · 2023Article
- Accelerometer-Assessed Physical Activity and Cognitive Performance among European Adults Aged 50+: The Mediating Effects of Social Contacts and Depressive Symptoms.Healthcare (Basel, Switzerland) · 2022Article
- Racial Segregation and Cognitive Function Among Older Adults in the United States: Findings From the Reasons for Geographic and Racial Differences in Stroke Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
- Status of Sedentary Time and Physical Activity of Rural Residents: A Cross-Sectional Population-Based Study in Eastern China.Frontiers in public health · 2022Observational
- Physical activity moderates the association between executive function and functional connectivity in older adults.Aging brain · 2022Article
- Processing speed mediates the association between physical activity and executive functioning in elderly adults.Frontiers in psychology · 2022Article
- Promoting brain health through physical activity among adults exposed to early life adversity: Potential mechanisms and theoretical framework.Neuroscience and biobehavioral reviews · 2021Review
- Cognitive Function is a Predictor of the Daily Step Count in Patients With Subacute Stroke With Independent Walking Ability: A Prospective Cohort Study.Archives of rehabilitation research and clinical translation · 2021Article
- Deducing the Impact of Physical Activity, Sedentary Behavior, and Physical Performance on Cognitive Function in Healthy Older Adults.Frontiers in aging neuroscience · 2021Article
- Physical Activity and Trajectory of Cognitive Change in Older Persons: Mayo Clinic Study of Aging.Journal of Alzheimer's disease : JAD · 2021Article
- Weather Woes? Exploring Potential Links between Precipitation and Age-Related Cognitive Decline.International journal of environmental research and public health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 2 countries.
Funding
Abstract
objectivesTo examine the relationship between objectively measured physical activity (PA) and cognitive function in white and black older adults.
designCross-sectional.
settingREasons for Geographic and Racial Differences in Stroke (REGARDS) study.
participantsOlder adults who provided valid data from accelerometer and cognitive function tests (N = 7,098). MEASUREMENTS: Accelerometers provided estimates of PA variables for 4 to 7 consecutive days. PA cut-points of 50 counts per minute (cpm) and 1,065 cpm were applied to differentiate between being sedentary and light PA and between light and moderate to vigorous PA (MVPA), respectively. Prevalence of cognitive impairment was defined using the Six-Item Screener (<4/6). Letter fluency, animal fluency, word list learning, and Montreal Cognitive Assessment (orientation and recall) were used to assess memory and executive function.
resultsOf 7,098 participants (aged 70.1 ± 8.5, 54.2% female, 31.5% black), 359 (5.1%) had impaired cognition within ±12 months of PA measurement. The average proportion of time spent in MVPA (MVPA%) was 1.4 ± 1.9%. Participants in the highest quartile of MVPA% (~258.3 min/wk) were less likely to be cognitively impaired than those in the lowest quartile (odds ratio = 0.65, 95% confidence interval = 0.43-0.97). MVPA% was also significantly associated with executive function and memory z-scores (P < .001). Similar analyses of proportion of time spent in light PA (LPA%) and sedentary time (ST%) showed no significant associations with cognitive function.
conclusionHigher levels of objectively measured MVPA%, rather than LPA% or ST%, were associated with lower prevalence of cognitive impairment and better performance in memory and executive function in aging people. The amount of MVPA associated with lower prevalence of cognitive impairment is consistent with meeting PA guidelines.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.