ArticlePloS one2015
Performance of a Knowledge-Based Model for Optimization of Volumetric Modulated Arc Therapy Plans for Single and Bilateral Breast Irradiation.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed.
- Article
- Implementation and Dosimetric Evaluation of a Knowledge-Based IMRT Model for Left-Sided Breast Radiotherapy with DIBH.Journal of applied clinical medical physics · 2026Article
- OVH-guided planning for superior heart and lung sparing in breast cancer radiotherapy.Journal of applied clinical medical physics · 2026Article
- Knowledge-based planning for intensity-modulated proton therapy of the breast and chest wall with regional lymph nodes: development, validation, and comparative evaluation of two models.Frontiers in oncology · 2026Article
- BreastWatch: A Varian Eclipse script tool for Community-Based automatic evaluation of breast treatment plans.Journal of applied clinical medical physics · 2025Article
- Pro-active risk analysis of an in-house developed deep learning based autoplanning tool for breast Volumetric Modulated Arc Therapy.Physics and imaging in radiation oncology · 2024Article
- Neural network dose prediction for cervical brachytherapy: Overcoming data scarcity for applicator-specific models.Medical physics · 2024Article
- Automated treatment planning for whole breast irradiation with individualized tangential IMRT fields.Journal of applied clinical medical physics · 2024Article
- Article
- A method for beam's eye view breath-hold monitoring during breast volumetric modulated arc therapy.Physics and imaging in radiation oncology · 2023Article
- Knowledge-based DVH estimation and optimization for breast VMAT plans with and without avoidance sectors.Radiation oncology (London, England) · 2022Article
- Domain knowledge driven 3D dose prediction using moment-based loss function.Physics in medicine and biology · 2022Article
- Training and validation of a knowledge-based dose-volume histogram predictive model in the optimisation of intensity-modulated proton and volumetric modulated arc photon plans for pleural mesothelioma patients.Radiation oncology (London, England) · 2022Article
- Knowledge-based automatic plan optimization for left-sided whole breast tomotherapy.Physics and imaging in radiation oncology · 2022Article
- Influence of Beam Angle on Normal Tissue Complication Probability of Knowledge-Based Head and Neck Cancer Proton Planning.Cancers · 2022Article
- Comparison of volumetric modulated arc therapy and intensity-modulated radiotherapy for left-sided whole-breast irradiation using automated planning.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022Article
- Performance of a knowledge-based planning model for optimizing intensity-modulated radiotherapy plans for partial breast irradiation.Journal of applied clinical medical physics · 2022Article
- Comprehensive nodal breast VMAT: solving the low-dose wash dilemma using an iterative knowledge-based radiotherapy planning solution.Journal of medical radiation sciences · 2022Article
- Artificial Intelligence in Radiation Therapy.IEEE transactions on radiation and plasma medical sciences · 2022Article
- Artificial intelligence applications in intensity modulated radiation treatment planning: an overview.Quantitative imaging in medicine and surgery · 2021Review
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the performance of a model-based optimisation process for volumetric modulated arc therapy, VMAT, applied to whole breast irradiation. METHODS AND MATERIALS: A set of 150 VMAT dose plans with simultaneous integrated boost were selected to train a model for the prediction of dose-volume constraints. The dosimetric validation was done on different groups of patients from three institutes for single (50 cases) and bilateral breast (20 cases).
resultsQuantitative improvements were observed between the model-based and the reference plans, particularly for heart dose. Of 460 analysed dose-volume objectives, 13% of the clinical plans failed to meet the constraints while the respective model-based plans succeeded. Only in 5 cases did the reference plans pass while the respective model-based failed the criteria. For the bilateral breast analysis, the model-based plans resulted in superior or equivalent dose distributions to the reference plans in 96% of the cases.
conclusionsPlans optimised using a knowledge-based model to determine the dose-volume constraints showed dosimetric improvements when compared to earlier approved clinical plans. The model was applicable to patients from different centres for both single and bilateral breast irradiation. The data suggests that the dose-volume constraint optimisation can be effectively automated with the new engine and could encourage its application to clinical practice.
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