ArticleSchizophrenia research2016
Deficient cortical face-sensitive N170 responses and basic visual processing in schizophrenia.
Article in Schizophrenia research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- A Systematic Review and Meta-Analysis on Contrast Sensitivity in Schizophrenia.Schizophrenia bulletin · 2025Pooled it
- Facial Emotion Recognition in Schizophrenia.Frontiers in psychiatry · 2021Pooled it
- The Balance in the Head: How Developmental Factors Explain Relationships Between Brain Asymmetries and Mental Diseases.Brain sciences · 2025Review
- Altered N170 and compensatory mechanisms in face processing in schizophrenia: an event-related potential study.Frontiers in psychiatry · 2025Article
- An ERP Study of Face Processing in Schizophrenia, Bipolar Disorder, and Socially Isolated Individuals from the Community.Clinical EEG and neuroscience · 2024Article
- Neurophysiological indices of face processing in people with psychosis and their siblings: An event-related potential study.The European journal of neuroscience · 2024Article
- The emotional facial recognition performance of Chinese patients with schizophrenia: An event-related potentials study.Indian journal of psychiatry · 2023Article
- Electrophysiological Studies of Reception of Facial Communication in Autism Spectrum Disorder and Schizophrenia.Review journal of autism and developmental disorders · 2022Article
- Facial emotion processing and language during early-to-middle childhood development: An event related potential study.Developmental cognitive neuroscience · 2022Article
- An Event-Related Potential Investigation of Early Visual Processing Deficits During Face Perception in Youth at Clinical High Risk for Psychosis.Schizophrenia bulletin · 2022Article
- Neurophysiological substrates of configural face perception in schizotypy.Schizophrenia research · 2020Article
- Abnormal Contingent Negative Variation Drifts During Facial Expression Judgment in Schizophrenia Patients.Frontiers in human neuroscience · 2020Article
- Neutral face and complex object neurophysiological processing deficits in long-term schizophrenia and in first hospitalized schizophrenia-spectrum individuals.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2019Article
- From basic perception deficits to facial affect recognition impairments in schizophrenia.Scientific reports · 2019Article
- Automatic Processing Advantage of Cartoon Face in Internet Gaming Disorder: Evidence From P100, N170, P200, and MMN.Frontiers in psychiatry · 2019Article
- Stimuli may have little impact on the deficit of visual working memory accuracy in first-episode schizophrenia.Neuropsychiatric disease and treatment · 2019Article
- Schizophrenia and Category-Selectivity in the Brain: Normal for Faces but Abnormal for Houses.Frontiers in psychiatry · 2018Article
- Diagnoses and characteristics of autism spectrum disorders in children with Prader-Willi syndrome.Journal of neurodevelopmental disorders · 2017Article
- Revealing the Dysfunction of Schematic Facial-Expression Processing in Schizophrenia: A Comparative Study of Different References.Frontiers in neuroscience · 2017Article
- Sluggishness of Early-Stage Face Processing (N170) Is Correlated with Negative and General Psychiatric Symptoms in Schizophrenia.Frontiers in human neuroscience · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundFace detection, an ability to identify a visual stimulus as a face, is impaired in patients with schizophrenia. It is unclear whether impaired face processing in this psychiatric disorder results from face-specific domains or stems from more basic visual domains. In this study, we examined cortical face-sensitive N170 response in schizophrenia, taking into account deficient basic visual contrast processing.
methodsWe equalized visual contrast signals among patients (n=20) and controls (n=20) and between face and tree images, based on their individual perceptual capacities (determined using psychophysical methods). We measured N170, a putative temporal marker of face processing, during face detection and tree detection.
resultsIn controls, N170 amplitudes were significantly greater for faces than trees across all three visual contrast levels tested (perceptual threshold, two times perceptual threshold and 100%). In patients, however, N170 amplitudes did not differ between faces and trees, indicating diminished face selectivity (indexed by the differential responses to face vs. tree).
conclusionThese results indicate a lack of face-selectivity in temporal responses of brain machinery putatively responsible for face processing in schizophrenia. This neuroimaging finding suggests that face-specific processing is compromised in this psychiatric disorder.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.