Evidence map›Paper›PMID 26690714›Full record

ArticlePediatric research2016

Association between allergic diseases and risks of HSP and HSP nephritis: a population-based study.

An-Chyi Chen, Cheng-Li Lin, Te-Chun Shen, Tsai-Chung Li, Fung-Chang Sung, Chang-Ching Wei

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Article in Pediatric research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
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10citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

An-Chyi ChenDepartment of Pediatric Medicine, Children's Hospital of China Medical University Hospital, Taichung, Taiwan.
Cheng-Li LinManagement Office for Health Data, China Medical University Hospital, Taichung, Taiwan.
Te-Chun ShenSchool of Medicine, China Medical University, Taichung, Taiwan.ORCID http://orcid.org/0000-0002-9427-1068
Tsai-Chung LiDepartment of Public Health, China Medical University, Taichung, Taiwan.
Fung-Chang SungDepartment of Public Health, China Medical University, Taichung, Taiwan.
Chang-Ching WeiDepartment of Pediatric Medicine, Children's Hospital of China Medical University Hospital, Taichung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome allergic inflammation-associated mediators have been reported in acute stage of Henoch-Schönlein purpura (HSP). However, the association of children with allergic diseases and their subsequent risks of HSP and HSP nephritis remain unknown.

methodsIn this study, we included 2,240 children with HSP diagnosed between 2000 and 2008 as well as 8,960 non-HSP controls matched for age, sex, and level of urbanization. The odds ratios (ORs) of HSP were calculated with respect to associations with pre-existing allergic diseases.

resultsChildren with allergic diseases had an increased subsequent risk of HSP; the lowest adjusted OR (aOR) was 1.33 for allergic conjunctivitis (95% confidence interval (CI): 1.17-1.52) and the highest was 1.68 for asthma (95% CI: 1.48-1.91). The aOR increased to 2.03 (95% CI: 1.80-2.31) in children with at least two allergic diseases. Children who visited medical institutes more often per year for associated allergic diseases had an increased risk of HSP. Of the 2,240 children with HSP, 249 (11%) had HSP nephritis and 45.8% of those with nephritis had history of any allergic disease.

conclusionAtopic children had an increased subsequent risk of HSP but not an increased risk of HSP nephritis.

Indexed as

Population SurveillanceChildChild, PreschoolFemaleHumansHypersensitivityIgA VasculitisMaleNephritis

Identifiers

PMID26690714

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