ArticleEnvironment international2016
Urinary concentrations of PAH and VOC metabolites in marijuana users.
Article in Environment international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 64 citations in OpenAlex.
- Urinary Cyanoethyl Mercapturic Acid, a Biomarker of the Smoke Toxicant Acrylonitrile, Clearly Distinguishes Smokers From Nonsmokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020Trial
- Cigarette Smokers Versus Cousers of Cannabis and Cigarettes: Exposure to Toxicants.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020Trial
- Procedural Challenges in the Analysis of Toxic Metals in Electronic Cannabinoid Delivery System Aerosols Produced for Vaping Cannabinoids.Journal of testing and evaluation · 2026Article
- Volatile Organic Compound Metabolites Are Found in the Urine of Breastfed Infants Whose Mothers Use Cannabis: The Lactation and Cannabis (LAC) Study.International journal of environmental research and public health · 2026Article
- Cannabis Use During Pregnancy Is Associated with the Suppression of Circulating Maternal Cytokines.Cannabis and cannabinoid research · 2026Article
- Prenatal cannabis smoke exposure alters placental development in a murine model of pregnancy.PloS one · 2026Article
- Article
- Alcohol and Cannabis Use Associated with Cardiometabolic Biomarkers among "All of Us" Cancer Survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Current marijuana use is associated with lower circulating α-Klotho levels in US adults even after adjusting for tobacco use: A national cross-sectional analysis of NHANES.Tobacco induced diseases · 2025Article
- Influence of Half-life and Smoking/Nonsmoking Ratio on Biomarker Consistency between Waves 1 and 2 of the Population Assessment of Tobacco and Health Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Human Exposure Levels of Volatile Organic Compounds in E-waste Recycling Area: Get Insight into Impacts of Manipulation Mode and Associations with Oxidative Stress Markers.Environment & health (Washington, D.C.) · 2023Article
- Furan Metabolites Are Elevated in Users of Various Tobacco Products and Cannabis.Chemical research in toxicology · 2023Article
- The exposure to volatile organic chemicals associates positively with rheumatoid arthritis: a cross-sectional study from the NHANES program.Frontiers in immunology · 2023Article
- Cigarette smoking is associated with acrylamide exposure among the U.S. population: NHANES 2011-2016.Environmental research · 2022Article
- Age groups differences in the prevalence and popularity of individual tobacco product use in young adult and adult marijuana and tobacco co-users and tobacco-only users: Findings from Wave 4 of the population assessment of tobacco and health study.Drug and alcohol dependence · 2022Article
- Optimal Cutoff Concentration of Urinary Cyanoethyl Mercapturic Acid for Differentiating Cigarette Smokers From Nonsmokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022Article
- Nonmedical Cannabis Use: Patterns and Correlates of Use, Exposure, and Harm, and Cancer Risk.Journal of the National Cancer Institute. Monographs · 2021Article
- The influence of demographic and lifestyle factors on urinary levels of PAH metabolites-empirical analyses of Cycle 2 (2009-2011) CHMS data.Journal of exposure science & environmental epidemiology · 2021Article
- Acrolein and other toxicant exposures in relation to cardiovascular disease among marijuana and tobacco smokers in a longitudinal cohort of HIV-positive and negative adults.EClinicalMedicine · 2021Article
- Association between Urinary Metabolite Levels of Organophosphorus Flame Retardants and Serum Sex Hormone Levels Measured in a Reference Sample of the US General Population.Exposure and health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundMarijuana is seeing increased therapeutic use, and is the world's third most-popular recreational drug following alcohol and tobacco. This widening use poses increased exposure to potentially toxic combustion by-products from marijuana smoke and the potential for public health concerns.
objectivesTo compare urinary metabolites of polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs) among self-reported recent marijuana users and nonusers, while accounting for tobacco smoke exposure.
methodsMeasurements of PAH and VOC metabolites in urine samples were combined with questionnaire data collected from participants in the National Health and Nutrition Examination Surveys (NHANES) from 2005 to 2012 in order to categorize participants (≥18years) into exclusive recent marijuana users and nonusers. Adjusted geometric means (GMs) of urinary concentrations were computed for these groups using multiple regression analyses to adjust for potential confounders.
resultsAdjusted GMs of many individual monohydroxy PAHs (OH-PAHs) were significantly higher in recent marijuana users than in nonusers (p<0.05). Urinary thiocyanate (p<0.001) and urinary concentrations of many VOC metabolites, including metabolites of acrylonitrile (p<0.001) and acrylamide (p<0.001), were significantly higher in recent marijuana users than in nonusers.
conclusionsWe found elevated levels of biomarkers for potentially harmful chemicals among self-identified, recent marijuana users compared with nonusers. These findings suggest that further studies are needed to evaluate the potential health risks to humans from the exposure to these agents when smoking marijuana.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.