Evidence map›Paper›PMID 26690442›Full record

ReviewSensors (Basel, Switzerland)2015

Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering.

Ana Rubina Perestrelo, Ana C P Águas, Alberto Rainer, Giancarlo Forte

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Review
  2. Skin-on-chip: Quo vadis?APL bioengineering · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Microfluidic Systems for Neural Cell Studies.Bioengineering (Basel, Switzerland) · 2023
    Review
  9. Article
  10. Advances in Regenerative Medicine and Biomaterials.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Selection of natural biomaterials for micro-tissue and organ-on-chip models.Journal of biomedical materials research. Part A · 2022
    Review
  16. Article
  17. Organ-On-A-Chip: A Survey of Technical Results and Problems.Frontiers in bioengineering and biotechnology · 2022
    Review
  18. Review
  19. Article
  20. Molecular Communications in Viral Infections Research: Modeling, Experimental Data, and Future Directions.IEEE transactions on molecular, biological, and multi-scale communications · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ana Rubina PerestreloInternational Clinical Research Center (ICRC), Integrated Center of Cellular Therapy and Regenerative Medicine (ICCT), St. Anne's University Hospital, Brno 656 91, Czech Republic. ana.rubina.perestrelo@fnusa.cz.
Ana C P ÁguasCenter for Biomedical Research, University of Algarve, Faro 8005-139, Portugal. acaguas@ualg.pt.
Alberto RainerTissue Engineering Unit, Università Campus Bio-Medico di Roma, Rome 00128, Italy. a.rainer@unicampus.it.
Giancarlo ForteInternational Clinical Research Center (ICRC), Integrated Center of Cellular Therapy and Regenerative Medicine (ICCT), St. Anne's University Hospital, Brno 656 91, Czech Republic. giancarlo.forte@fnusa.cz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in biomedical technologies are mostly related to the convergence of biology with microengineering. For instance, microfluidic devices are now commonly found in most research centers, clinics and hospitals, contributing to more accurate studies and therapies as powerful tools for drug delivery, monitoring of specific analytes, and medical diagnostics. Most remarkably, integration of cellularized constructs within microengineered platforms has enabled the recapitulation of the physiological and pathological conditions of complex tissues and organs. The so-called "organ-on-a-chip" technology, which represents a new avenue in the field of advanced in vitro models, with the potential to revolutionize current approaches to drug screening and toxicology studies. This review aims to highlight recent advances of microfluidic-based devices towards a body-on-a-chip concept, exploring their technology and broad applications in the biomedical field.

Indexed as

Microfluidic Analytical TechniquesModels, BiologicalTissue Array AnalysisTissue EngineeringAnimalsBiomedical ResearchHumansMiceMicro-Electrical-Mechanical SystemsBioMEMsbody-on-a-chipmicrofluidicsorgan-on-a-chiptissue engineering

Identifiers

PMID26690442
PMCPMC4721768

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.